CA125 is the most widely used tumour marker in ovarian cancer with unsatisfactory sensitivity and specificity especially at early stage. It is quantified by antibody-based immunoassays; however different molecular weight isoforms have been described in the literature which have never been validated by mass spectrometry, potentially affecting the diagnostic accuracy and clinical reliability of t...

Tooth size varies exponentially with body weight in primates. Logarithmic transformation of tooth crown area and body weight yields a linear model of slope 0.67 as an isometric (geometric) baseline for study of dental allometry. This model is compared with that predicted by metabolic scaling (slope = 0.75). Tarsius and other insectivores have larger teeth for their body size than generalized pr...

NAD(P)H quinone oxidoreductase 1 (NQO1) is an enzyme capable of reducing a broad range of chemically reactive quinones and quinoneimines (QIs) and can be strongly upregulated by Nrf2/Keap1-mediated stress responses. Several commonly used drugs implicated in adverse drug reactions (ADRs) are known to form reactive QI metabolites upon bioactivation by P450, such as acetaminophen (APAP), diclofena...

BACKGROUND AND OBJECTIVES Laparoscopic treatment of hydatid disease of the liver produces encouraging results, though its feasibility and safety have been questioned. We evaluated the feasibility and safety of laparoscopic management of hydatid disease of the liver. METHODS Consecutive patients with this disease reporting to our department from August 1998 to January 2002 were offered laparos...

Let X and id="M4"> ∗ be a Banach space its dual, respectively. In this paper, we study the relations between modulus of id="M5"> W 1 ε id="M6"> ζ in id="M7"> normal structure id...

There is a long standing conjecture that there are at least \begin{document}$ n $\end{document} closed characteristics on any compact convex hypersurface id="M4">\begin{document}$ \Sigma in id="M5">\begin{document}$ \mathbb{R}^{2n} $\end{document}. In this paper, we provide som...

This paper investigates how oil price (OP) influences the prospects of green bonds by utilising quantile-onquantile (QQ) method and researching interactions between OP bond index (GBI) from 2011:M1 to 2021:M11. We find that impacts on GBI are positive in short run. The effects indicate high can promote development market, indicating be considered an asset avoid shocks. However, medium long term...

In this paper, we characterize w -Noetherian rings and SM rings. More precisely, in terms of the id="M3"> u -operation on a commutative ring id="M4"> R , prove that id="M5"> is id="M6"> if only direct limit id="M7"> r GV -torsion-free injective id="M8"> -modules id="M9"> SM, whic...

In order to achieve profit goals, in a situation of growing competition, and with a decreasing interest rate spread, it is becoming increasingly important for banks to optimise their cost performance. The first requisite for this is to have a reliable, analytical system of cost measurement, especially for those costs which are difficult to determine, like the indirect operating costs. Tradition...

BACKGROUND Since the use of pneumococcal conjugate vaccines PCV7 and PCV13 in children became widespread, invasive pneumococcal disease (IPD) has dramatically decreased. Nevertheless, there has been a rise in incidence of Streptococcus pneumoniae non-vaccine serotypes (NVT) colonising the human nasopharynx. Nasopharyngeal colonisation, an essential step in the development of S. pneumoniae-induc...