the macrocyclic ligands 2,3,5,6-bis{3’-bromo-5’-tert-butyl benzo-5-phenyl benzo} 12c3 (l1), 2,3,5,6-bis{3’-bromo-5’-tert butyl-benzo-5’-phenyl-benzo}15c4 (l2), 2,3,5,6-bis{3’-bromo-5’-tert butyl-benzo-5’-phenyl-benzo}18c5 (l3) have been synthesized and their alkaline metal compounds with naclo4∙h2o and kclo4  have been prepared. chemical formulas of all compounds have been characterized by usin...

The increase of the ionic strength amplifies the species bearing acidic side chains from a bio-inspired dynamic combinatorial library of macrocyclic pseudopeptides, in close resemblance to the evolution observed for the proteins of halophilic microorganisms.

A practical and modular approach to obtain a diverse set of 14-membered macrocyclic compounds from carbohydrates is developed that utilizes functional groups at C-1 and C-5. The evaluation of this toolbox in various zebrafish assays led to the identification of 2.7f as an antiangiogenesis agent.

The field of heteropolymetallic complexes is of current interest in connection with the structures and roles of polymetallic active sites in biological systems [1], and the design of new molecular materials with magnetic, optical and electrical properties [2,3]. Among various relevant systems, oxamido-bridged polynuclear complexes [2,4] and phenolato-oxygen-bridged macrocyclic complexes [5,6] r...

Nephrogenic systemic fibrosis (NSF) is a disease with progressive fibrosis. We describe two cases of NSF after exposure to a macrocyclic gadolinium-based contrast agent (GBCA) gadobutrol, which has been considered as a low-risk agent compared to linear GBCAs. The first case had chronic kidney disease (CKD) Stage 3 and was exposed to 17.5 ml of gadobutrol. The second case has been exposed twice ...

Two thread-shaped cations, pyridinium nicotinamide and imidazolium, as their chloride and hexafluorophosphate salts, were studied with regards to complexation with hydrogen-bond-donating acyclic and macrocyclic ligands. In the latter case, the cations form pseudorotaxanes templated by the chloride anion but not hexafluorophosphate. This formation is a function of the coupling of ion-pairing bet...