provided the original work is properly cited. CC Acromegaly is a condition caused by an excessive secretion of growth hormones [1]. Hypertrophy in the face and extremities can cause enlarged lower jaws, macroglossia, and thickened pharyngeal and laryngeal soft tissues [2]. Hypertrophy in the vocal cord can lead to changes in the upper airway, making airway management difficult during trachea in...

OBJECTIVES/HYPOTHESIS To identify a clinical predictor score for difficult laryngeal exposure (DLE) during operative microlaryngoscopy. STUDY DESIGN Prospective cohort study in two academic institutions. METHODS We evaluated 319 patients before microlaryngoscopy for benign and malignant glottic diseases by a standardized preoperative assessment protocol (Laryngoscore) that included 11 param...

AIMS Oral amyloidosis is a rare and debilitating disease that, whether primary or secondary, may severely impact the quality of a patient's life. The study investigated the characteristics of amyloid deposition in the tongue from the clinical and histopathological profiles. MATERIALS AND METHODS Biopsy specimens were received from five patients: 2 female, 3 male. All biopsies were taken from ...

The anatomical states of the oral cavity and pharynx during mouth breathing in children with adenoid hypertrophy and in adults confirmed the speculation that mouth breathing is disadvantageous compared with nose breathing. In addition, comparison of the anatomical state between wakefulness and sleep in normal adults showed slight depression of the tongue root and slight narrowing of the orophar...

Lymphangiomas are rare congenital malformations which are commonly seen in the head and neck region. The disease can be histologically differentiated from other vascular disorders such as cavernous or capillary hemangioma with the lymphatic endothelium-lined cystic spaces. The onset of lymphangiomas are either at birth (60 to 70%) or up to two years of age (90%). It is rare in adults. The thera...

We report on a female patient with Dandy-Walker malformation possibly caused by heterozygous loss of ZIC1 and ZIC4. The patient presented with mental retardation, epilepsy, and multiple congenital malformations including spina bifida, mild dysmorphic facial features including, thick eyebrows, broad nose, full lips, macroglossia, and hypoplasia of the cerebellar vermis with enlargement of the fo...

BeckwithWiedemann syndrome, characterized by the triad of omphalocele, macroglossia, and gigantism, has a population incidence estimated at 1/13,700. This is likely an underestimate, because individuals with milder phenotypes may not be diagnosed. Some cases of isolated hemihyperplasia may, in fact, represent BeckwithWiedemann syndrome with reduced expressivity. Additional clinical features of ...

Primary systemic amyloidosis is a rare disorder characterized by multisystemic homogenous hyaline amyloid material. We report a case of 68 years old male presented with generalized weakness, fatigue, anorexia and impaired taste sensation. Muco-cutaneous lesions like, macroglossia with bullous haemorrhagic lesions, peri-orbital purpura, and nail changes were present. He had no cardiomegaly, hepa...

OBJECTIVE AND IMPORTANCE To report a case of the bilateral transposition of the maxillary canines with the premolars in a 17-year-old female with Down syndrome. CLINICAL PRESENTATION AND INTERVENTION A 17-year-old female presented with moderate mental retardation; she was short and of small stature, and she had a round cherubic face and a broad forehead. Clinical intraoral examination reveale...