Background: Atrial fibrillation (AF) is the most common arrhythmia in patients with β-thalassemia major (β-TM) due to cardiac iron overload. AF may be predicted by changes in P wave parameters. The aim of this study was to evaluate the correlation between P-wave parameters and atrial markers with mean serum ferritin levels measured yearly. Methods: Fifty patients with β-TM and 50 healthy subje...

BACKGROUND & OBJECTIVES The amount of foetal haemoglobin that persists in adulthood affects the clinical severity of haemoglobinopathies including β-thalassaemia major and sickle cell anaemia (SCA). The present study was undertaken to analyse β-thalassaemia as well as SCA patients for the single nucleotide polymorphism (SNP), rs11886868 (T/C) in BCL11A gene and to evaluate the association betwe...

it has been investigated the in vitro antioxidant properties of ethanol extracts of the contained-allantoin plants in this study. contained-allantoined plant samples plantago lanceolata, plantago major, robinia pseudoacacia, platanus orientalis and aesculus hippocastanum were tested at different concentrations. the antioxidant activities of plant samples were analysed by 1,1- diphenyl-2-picrylh...

Background & Aim: Salvia spinosa L. is a perennial shrub and aromatic plant belongs to the family Lamiaceae. S. spinosa grows wild in some districts of Iran. The aim of this study was to identify of the chemical components of S. spinosa in Isfahan climatic conditions. Experimental: The aerial parts of the plants were collected from Isfahan province in 2014. The essen...

To estimate the levels of folic acid, vitamin B12 and their relationship with ferritin in βthalassemia major children. Thirty children with β-thalassemia major in the age group of 4 to 8 years were studied for estimation of serum ferritin, folic acid and vitamin B12 over a period of one year. These tests were determined by means of Immulite 1000 analyzer. The statistical analysis of β-thalassem...