Preventing premature interaction of pre-ribosomes with the translation apparatus is essential for translational accuracy. Hence, final maturation step releasing functional 40S ribosomal subunits, namely processing 18S RNA 3? end, safeguarded by protein DIM2, which both interacts endoribonuclease NOB1 and masks rRNA cleavage site. To elucidate control mechanism that unlocks activity, we performe...

Glutamatergic inputs clustered over ~20-40 μm can elicit local NMDA spike/plateau potentials in terminal dendrites of cortical pyramidal neurons, inspiring the notion that a single terminal dendrite can function as a decision-making computational subunit. A typical terminal basal dendrite is ~100-200 μm long: could it function as multiple decision-making subunits? We test this by sequential foc...

The adenosine 3’,5’-monophosphate-dependent (CAMPdependent) protein kinases of rabbit skeletal muscle have been partially characterized in terms of molecular size and subunit composition. Three and possibly four species of protein kinase have been detected. The largest form of the enzyme was estimated by gel filtration and sedimentation to have a molecular weight of 123,000 and to be made up of...

PURPOSE To review the involvement of the ion transporter Na+/K+-ATPase (NaK) in the migration and proliferation of glioma cells. Preliminary studies indicate that NaK alpha1 subunits seem to be upregulated in a proportion of glioblastomas but not in normal brain tissues. DESIGN The present review focuses on (1) the natural resistance of migrating malignant glioma cells to apoptosis, (2) autop...

Ecdysis in arthropods is a complex process, regulated by many neurohormones, which must be released in a precisely coordinated manner. In insects, the ultimate hormone involved in this process is the cuticle tanning hormone, bursicon. Recently, this hormone has been identified in crustaceans. To further define the distribution of bursicon in crustacean nervous systems, and to compare hormone st...

in this study, 120 accessions of aegilops crassa collected from various geographical areas of iran were analyzed with respect to genome size and protein markers. a flow cytometry survey of these accessions revealed that one hundred and thirteen of the accessions were tetraploid and seven were hexaploid. moreover, these accessions revealed variations in high molecular weight glutenin subunit com...

background: the presence of rennin-angiotensin components in mammalian ovaries and their involvement in ovarian physiology have been established. in the present study, effects of angiotensin ii (ang ii) on sodium-potassium adenosine triphosphatase (na+/k+/atpase) expression and development of sheep embryos was evaluated. methods: the abattoir-derived cumulus oocyte complexes (coc) were randomly...