The reproductive activity in male mammals is well known to be regulated by the hypothalamus-pituitary- gonad axis. The hypothalamic neurons secreting gonadotropin releasing hormone (GnRH) govern the reproductive neuroendocrine system by integrating all the exogenous information impinging on themselves. The GnRH synthesized and released from the hypothalamus arrives at the anterior pituitary thr...

The general effects of castration, in addition to the loss of spermatogenesis, have been known since our earliest historical records. It is not the purpose of this paper to review the earlier studies which emphasize the effects of castration of the male, of transplantation of gonads, and of cryptorchidism on the various physiological, psychical, morphological, and histological changes in the bo...

background: high content of phospholipids in testes and epididymis is involved in regulation of spermatogenesis. on the other side, it makes testes susceptible to oxidative stress due to lipid peroxidation, which alters the normal mechanism of spermatogenesis. objective: in the present investigation, antioxidant effects of ethanolic extracts of parsley, lettuce and brahmi were tested against d-...

In many insects, the accessory gland, a secretory tissue of the male reproductive system, is essential for male fertility. Male accessory gland is the major source of proteinaceous secretions, collectively called as seminal proteins (or accessory gland proteins), which upon transfer, manipulate the physiology and behavior of mated females. Insect hormones such as ecdysteroids and juvenoids play...

BACKGROUND Diminished libido and sexual dysfunction are unusually common among male epileptic patients. The most important etiologic factor may be antiepileptic drugs (AEDs)-induced androgen deficiency. We compared reproductive hormone levels among men with epilepsy taking various AEDs and normal controls. METHODS Subjects were 59 male epileptic patients who aged 24 ± 5 years. They had been r...

OBJECTIVE To evaluate the health effects of parental dietary exposure to GM rice TT51 on the male reproductive system of rat off spring. METHODS Rice-based diets, containing 60% ordinary grocery rice, MingHui63, or TT51 by weight, were given to parental rats (15 males/30 females each group) for 70 days prior mating and throughout pregnancy and lactation. After weaning, eight male offspring ra...

background: besides the well-known adverse effects of valproate (vpa), disorders related to male reproductive functions have been reported. furthermore, only a limited number of previous studies have reported the relationship between vpa dose and impairment of the hormonal axis and semen quality. a patient with reversible changes that occurred in the sperm parameters after a dose increment of v...