Psychological distress is common in patients with soft tissue and bone tumors. We first investigated its frequency the associated risk factors pre-operative Participants included 298 tumors who underwent surgery our institution between 2015 2020. was evaluated by Distress Impact Thermometer (DIT) that consists of two types questions (questions about severity patient’s (DIT-D) impact (DIT-I)). u...

adenoid cystic carcinoma (adcc) is a malignant neoplasm, which accounts for 5-10% of all salivary gland tumors (1). about 50% of these tumors originate from intraoral minor salivary glands usually in the hard palate (1). three clinically obvious characteristics of adcc include slow growth rate, perineural invasion and high incidence of distant metastasis (1). the most commonly-affected sites of...

The use of bone turnover markers in oncology includes monitoring of anticancer treatment in patients with malignant disease metastatic to the bones (therapeutic monitoring), predicting the risk of bone relapse in patients with a first diagnosis of potentially curative, early-stage malignant tumors (prognostic use), and making an early diagnosis of (microscopic) malignant bone disease in patient...

The present study aimed to investigate the imaging characteristics of primary malignant bone tumors in children. The imaging results of 34 children with primary malignant bone tumors confirmed by histopathological diagnosis between March 2008 and January 2014 were retrospectively analyzed. In total, 25 patients had osteosarcoma, with radiography and computed tomography (CT) showing osteolytic b...

Sclerostin (SOST) is an extracellular Wnt signaling antagonist which negatively regulates bone mass. Despite this, the expression and function of SOST in skeletal tumors remain poorly described. Here, we first describe the immunohistochemical staining pattern of SOST across benign and malignant skeletal tumors with bone or cartilage matrix (n=68 primary tumors). Next, relative SOST expression w...

this study aimed to investigate the frequency of varicella zoster virus (vzv) in benign and malignant breast tumors. a total of 24 carcinomas and 24 fibroadenomas paraffin embedded tumoral tissue samples were obtained from the pathology sections of toos and firoozgar hospitals in tehran, iran. all samples were collected from patients from june 2011 to february 2012. dna was extracted from all s...

Participant in the process of normal bone remodeling is vitamin D, which, addition, has antiinflammatory (anti-cytokine), anti-proliferative and anti-tumor effects. Objective study to assess level 25-hydroxyvitamin D3 concentration blood serum before start treatment patients with benign, primary malignant metastatic tumors, taking into account polymorbidity. Materials methods. The following wer...