Background and Objective: The primary goal of this study is to develop a rigorous understanding ofthe correlation between COX-2 expression and malignant melanoma prognostic factors. Material and Methods: In this cross-sectional study, we analyzed 60 cases of cutaneous malignant melanoma. The related stained slides were reviewed by two pathologists. The re...

Granular cell tumor is a rare benign non-encapsulated tumor that mostly presents in oral cavity. Breast localization is uncommon and occurs in about one per 1000 cases of breast cancers. It mainly affects premenopausal women showing the possible role of estrogen and progesterone levels in the progression of this tumor. Granular cell tumor is a great emulator of the invasive ductal carcinoma of ...

background: medulloblastoma is the most common malignant brain tumor in children. the important factors in predicting survival are the extent of disease, proliferation index of the tumor cells, histopathologic class and the age at diagnosis. the percentage of ki-67 positive cells reflects the proliferation  of the cells and is one of the critical factors which determine the growth of the tumor....

littoral cell angioma is a splenic vascular tumor of splenic sinus lining cells that is considered benign in general. this report describes a case of littoral cell angioma with no malignant histological features. the lesion is composed of anastomosing vascular channels resembling splenic sinus; they are lined by endothelial cells which show mitotic activity very rare. immunohistochemically, the...

granular cell tumor is a rare benign neoplasm most commonly appears in the head and neck region, especially in the tongue, cheek mucosa, and palate. occurrence in limbs is even rarer. these tumors account for approximately 0.5% of all soft tissue tumors. granular cell tumor can also affect other organs including skin, breast, and lungs. local recurrence and metastasis is potentially higher in m...

Background: Malignant neoplasms remain the second leading cause of death in children after accidents. The aim of this study was to assess the epidemiology of childhood cancer in children admitted to Dr sheikh hospital, Iran. Materials and Methods: This descriptive cross- sectional study had been done in Dr Sheikh Hospital in Mashhad University of medical science on 1764 children younger than 1...

Abstract Background Cerebral neoplasm arises from brain, spinal cord and meningeal cells. Not only malignant cerebral neoplasm also benign tumor could lead to death due to mass effect on vital structures. Access to these tumors is difficult, and MRI and CT scan could be helpful in determining anatomical location of tumors and distinction of malignant from benign. Objective For better and ea...