نتایج جستجو برای: mannose binding lectin gene
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Article history: Received 21 June 2016 Accepted 21 June 2016 Available online 23 June 2016 (Akira et al., 2006). Innate immunity relies on the binding of PAMPs to receptors on immune cells and to serum proteins, such as mannosebinding lectin (Akira et al., 2006; Ip et al., 2009). Cartwright et al. developed an ELISA using an engineered immunoglobulin domain fused to domains of mannose-binding l...
Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy of the immune system. Ongoing research attempt to illuminate at which conditions MBL deficiency m...
Codakine is an abundant 14-kDa mannose-binding C-type lectin isolated from the gills of the sea bivalve Codakia orbicularis. Binding studies using inhibition of hemagglutination indicated specificity for mannose and fucose monosaccharides. Further experiments using a glycan array demonstrated, however, a very fine specificity for N-linked biantennary complex-type glycans. An unusually high affi...
A gene encoding a mannose-binding lectin, Pinellia pedatisecta agglutinin (PPA), was isolated from leaves of Pinellia pedatisecta using genomic walker technology. The ppa contained an 1140-bp 5'-upstream region, a 771-bp open reading frame (ORF) and an 829-bp 3'-downstream region. The ORF encoded a precursor polypeptide of 256 amino acid residues with a 24-amino acid signal peptide. There were ...
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