This paper mainly examined the anti-osteosarcoma activity of total flavonoids extract from traditional Chinese medicine, nidus vespae. Orthogonal design was used to design the extraction process of total flavonoids. L(3(4)) orthogonal test was performed and the extracts obtained by three optimal extraction processes were used for anti-tumour activity screening in order to determine the optimal ...

When orchards reach the end of the productive cycle, the stumps removal becomes a mandatory operation to allow new soil preparation and to establish new cultivations. The exploitation of the removed stump biomass seems a valuable option, especially in the growing energy market of the biofuels; however, the scarce quality of the material obtained after the extraction compromises its marketabilit...

Objectives The present paper reports data of a randomized study aimed to analyse and compare the histologic and histomorphometric aspects of bone healing in extraction sites covered with collagen membrane alone or associated with porcine-derived bone graft. Material and Methods Thirty patients, with single extraction sockets without severe bone wall defects in the premolar/molar region, were ...

Flavonoids from Sophora flavescens were selectively extracted by mechanochemical-promoted extraction technology (MPET) after using response surface methodology to determine the optimal extraction parameters. The highest yield of 35.17 mg/g was achieved by grinding the roots with Na₂CO₃ (15%) at 440 rpm/min for 17.0 min and water was used as the sole solvent with a ratio of solvent to solid mate...

PURPOSE Soft tissue closure is mandatory for optimal healing of extraction sites treated via guided bone regeneration. The objective of this study was to evaluate the efficacy of a flap design based on the extension of palatal tissues to obtain and maintain soft tissue coverage over grafted extraction sockets. MATERIALS AND METHODS Adult patients (n = 22) with at least two teeth indicated for...

Matrix effect on mass spectrometry response was investigated with commercially available electrospray ionisation (ESI) and atmospheric pressure chemical ionisation (APCI) sources coupled with a single quadruple mass spectrometer. A post-column infusion system was used to observe the MS signal alterations of methadone, selected as the model compound, in plasma. For this purpose, two sample prepa...