"/^OME to breezy, bracing Black-^ pool"?this and other publicity phrases to thousands of people, not only in England but throughout the world, means the Golden Mile, with its side shows and sea food stalls, golden sands, the Tower or perhaps the Winter Gardens, a superb setting for national and international conferences. But the picture we see covers a much wider canvas, the area of the Blackpo...

Dr. Gaetano Santulli is a physician scientist (cardiologist) working at Columbia University Medical Center in New York (NY). He earned his MD and PhD from the University of Naples “Federico II”, followed by a postdoctoral fellowship at Columbia University. He has expertise in both clinical and basic research. His research interests include heart failure [1-3], diabetes mellitus [4, 5], adrenerg...

Dengue is a viral disease spread by mosquitos. Although most commonly occurring in the tropics, there has been a worldwide increasing geographic expansion and the World Health Organization considers half the world at risk for infection (http://www. who.int/mediacentre/factsheets/fs117/en/). Severe dengue (previously known as dengue haemorrhagic fever) is relatively common (;500 000 cases each y...

Arithmetic in large ring and field extensions is an important problem of symbolic computation, and it consists essentially of the combination of one multiplication and one division in the underlying ring. Methods are known for replacing one division by two short multiplications in the underlying ring, which can be performed essentially by using convolutions. However, while using school-book mul...

Celine Lefebvre is a computational biologist with research goals directed towards the identification of biomarkers and therapeutic targets for cancer by developing innovative statistical and computational methods. Specialist of the inference and interrogation of gene regulatory networks, she has developed a method for the identification of master regulators of physiological and pathological cel...

This issue will feature a different Editor’s message, as Neurology® Neuroimmunology & Neuroinflammation (N2) transitions to a new Editor, Dr. Josep Dalmau. Dr. Dalmau is a remarkable clinician-scientist-scholar who additionally carries the distinction of being transcontinental, holding positions at the University of Barcelona in Catalonia, Spain, and at the University of Pennsylvania. His disti...

The field of neuroscience has always been attractive to engineers. Neurons and their connections, like tiny circuit elements, process and transmit information in a dramatic way that is intimately curious to researchers in the computer science and engineering fields. Of particular interest has been the recent push in applying microtechnology to the field of neuroscience. This review is meant to ...

What is molecular medicine? My view is that it is the scientific discipline that applies the tool-box of molecular biology to understand the pathogenesis of disease. Ideally such work translates into novel diagnostics and novel drug targets and treatments. It is clear that molecular medicine is not only borrowing knowledge and tools from other life sciences, but the field is itself also driving...

We present a model of opinion dynamics in which agents adjust continuous opinions as a result of random binary encounters whenever their difference in opinion is below a given threshold. High thresholds yield convergence of opinions toward an average opinion, whereas low thresholds result in several opinion clusters. The model is further generalized to network interactions, threshold heterogene...

David P. Wolfer (born 1960) has been associate professor of anatomy at the Institute of Anatomy at the University of Zurich and at the Institute for Human Movement Sciences at ETH Zurich since 2005. He studied medicine in Zurich and got his doctorate in 1988. His research group investigates the biological basis of cognitive functions, in particular the role of the hippocampus in memory and cont...