BACKGROUND The etiology of pancreatic cancer remains elusive. Several studies have suggested a role for diabetes mellitus, but the magnitude of its contribution remains controversial. OBJECTIVES Utilizing a large administrative database, this retrospective cohort study was designed to investigate the relationship between type 2 diabetes mellitus and pancreatic cancer. PATIENTS AND DESIGN Us...

OBJECTIVE To gather current information about the effects of type 1 diabetes mellitus on children's cardiac autonomic behavior. DATA SOURCES The search of articles was conducted on PubMed, Ibecs, Medline, Cochrane, Lilacs, SciELO and PEDro databases using the MeSH terms: "autonomic nervous system", "diabetes mellitus", "child", "type 1 diabetes mellitus", "sympathetic nervous system" and "par...

Abnormal maternal glucose regulation occurs in 3-10% of pregnancies, and gestational diabetes mellitus (GDM), which is defined as glucose intolerance of variable degree with onset or first recognition during pregnancy, accounts for 90% of cases of diabetes mellitus (DM) in pregnancy. However, the rising prevalence of diabetes mellitus—21 million people (7% of the population) have some form of d...

In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group (group I, n = 12), (2) gestational diabetes mellitus rats as the control group (group II, n = 11), and (3) rats of normal pregnancy group (group III...

Type 2 diabetes mellitus and heart failure (HF) commonly coexist, with diabetes mellitus occurring in ≈25% of patients with chronic HF and ~40% in those hospitalized with acute HF. Importantly, the presence of diabetes mellitus in HF is associated with reduced survival and increased rates of hospitalization compared with HF patients without diabetes mellitus. Despite the common and dangerous co...

There are many studies documenting that diabetes mellitus is associated with cardiovascular diseases. Diabetes mellitus has a significant role and is an important risk factor in cardiovascular manifestations in patients with diabetes mellitus. Cardiovascular diseases are one of the main causes of morbidity and mortality in diabetic patients. Diabetes mellitus can affect performance, constructio...

CONTEXT Chronic pain is often present in patients with diabetes mellitus. OBJECTIVE To assess the effects of osteopathic manual treatment (OMT) in patients with diabetes mellitus and comorbid chronic low back pain (LBP). DESIGN Randomized, double-blind, sham-controlled, 2×2 factorial trial, including OMT and ultrasound therapy (UST) interventions. SETTING University-based study in Dallas-...

The global prevalence of diabetes mellitus among adults has risen from 4.7% in 1980 to 8.5% in 2014, increasing the number of adults with diabetes mellitus to a staggering 422 million worldwide, according to the World Health Organization. For comparison, this number is larger than the total population of the United States. Diabetes mellitus not only reduces quality of life and life expectancy, ...

BACKGROUND Mesangial enlargement (ME) is one of the hallmark lesions of diabetic nephropathy and plays a major role in diabetic renal failure. Conventional treatment of type 1 diabetes mellitus with insulin injections, diet, and medications has often failed to prevent development and progression of ME, presumably because of difficulty in achieving tight metabolic control. Although many pancreas...