This video presentation was created to show a method of harvesting the two most important highly vascular structures, not residing within the brain proper, that support forebrain function. They are the cerebral surface (superficial) vasculature along with associated meninges (MAV) and the choroid plexus which are necessary for cerebral blood flow and cerebrospinal fluid (CSF) homeostasis. The t...

DESCRIPTION A 32-year-old lady presented with a 7-month history of gradually progressive, areflexic, asymmetric-onset, sensorimotor paraparesis accompanied by bowel and bladder involvement. She had previously been diagnosed with tuberculous meningitis, for which she completed a course of antituberculosis treatment (2 months—isoniazid, rifampicin, pyrazinamide, streptomycin; 7 months—isoniazid, ...

Contrast material enhancement for cross-sectional imaging has been used since the mid 1970s for computed tomography and the mid 1980s for magnetic resonance imaging. Knowledge of the patterns and mechanisms of contrast enhancement facilitate radiologic differential diagnosis. Brain and spinal cord enhancement is related to both intravascular and extravascular contrast material. Extraaxial enhan...

tions on more recently autopsied patients. Special consideration was given to the frequency of leukemic cell involvement of the brain and meninges and the effects of anti-leukemic chemotherapy on the amount and distribution of leukemic cells in the central nervous system at the time these patients died. The material from man was also compared with that from mice given inoculations of L1210 leuk...

Neisseria meningitidis is remarkable for the diversity of interactions that the bacterium has with the human host, ranging from asymptomatic nasopharyngeal colonisation affecting virtually all members of the population; through focal infections of the meninges, joints, or eye; to the devastating and often fatal syndrome of meningococcal septic shock and purpura fulminans.

A neutropenic child of 20 months suffered generalized infection with Pseudomonas aeruginosa, involving the bloodstream and the meninges. This was successfully treated with intravenous and intrathecal antibiotics and granulocyte transfusions before granulopoiesis recovered spontaneously. No immunoglobulin replacement was given during the acute episode, as the diagnosis of X-linked hypogammaglobu...