INTRODUCTION Meningiomas are the most frequent group of intracranial tumours, accounting for around a third of all primary brain tumours. In most cases, they are benign neoplasms that start in the cells of the arachnoid mater and may be located in the intracranial and spinal cavities. AIM To perform a review of the information available on intracranial meningiomas that allows us to update cur...

Meningiomas are common intracranial tumours that arise from arachnoidal cells. Clinically they often manifest by headache, focal or generalized seizures, or neurologic deficits as a result of brain compression. More than 90 percent of these mostly slow growing meningiomas are benign. In symptomatic patients a resection should be performed with the intention to cure or at least alleviate symptom...

We describe a rare case of non-Langerhans histiocytosis, consistent with Erdheim-Chester disease (ECD), which presented with lesions resembling multiple meningiomas. The patient was initially evaluated for migraine headaches. Initial MR imaging demonstrated a parasellar mass and a second mass near the torcula considered to represent meningiomas. Within 1 year, he developed bilateral orbital les...

Orbital meningiomas generally arise from the sphenoid and cause ophthalmic problems by virtue of an expanding mass near the orbital apex. These benign tumours often have a soft tissue component within the orbit, cranium, or temporalis fossa (Fig 1) and may induce hyperostosis of the postero-lateral wall of the orbit. Symptoms are generally caused by displacement of the globe-with diplopia or pr...

Meningiomas are extraaxial central nervous system tumors most often discovered in middle to late adult life, and are more often seen in women. Ninety percent of meningiomas are benign, 6% are atypical, and 2% are malignant. Most patients in whom a meningioma is diagnosed undergo resection to relieve neurological symptoms. Complete resection is often curative. For the majority of incompletely re...

Meningiomas presenting as an intracranial neoplasm are relatively common. (15–18%).However, primary extracranial (ectopic, extracalvarial) meningiomas of the ear and temporal bone are rare, making up for less than 1% of all meningiomas. 1 The known female preponderance of intracranial meningiomas is also seen in the external auditory canal meningioma. They may be primary (very rare) or secondar...

Meningiomas are benign tumors of mesodermal origin that arise from arachnoid cell clusters that penetrate the dura to form arachnoid villi. These neoplasms represent one of the most common neoplasms developing within the central nervous system and are usually located at points of entry of vessels and nerves through the dura. Extracranial meningiomas (EM) comprise only 2% of all meningiomas, and...

The authors assessed 116 cases of meningiomas classified as typical, atypical and anaplastic and they used an immunohistochemical technique for estrogen and progesterone receptors attempting to determine if there is any difference between typical and non-typical tumors in relation to hormone receptors. The immunohistochemical technique to estrogen receptors was negative in all meningiomas studi...

UNLABELLED Atypical/anaplastic (World Health Organization (WHO) grades II and III) are less common and have poorer outcomes than benign meningiomas. This study aimed to analyze the outcome of patients with these tumors. METHOD Overall/recurrence-free survivals (RFS) and the Karnofsky Performance Scale of 52 patients with grades II (42) and III (9) meningiomas surgically treated were analyzed ...

Most meningiomas are benign, but some clinical-aggressive tumors exhibit brain invasion and cannot be resected without significant complications. To identify molecular markers for these clinically-aggressive meningiomas, we performed microarray analyses on 24 primary cultures from 21 meningiomas and 3 arachnoid membranes. Using this approach, increased transglutaminase 2 (TGM2) expression was o...