background: effects of estrogen on bone metabolism and its protective role on prevention of osteoporosis are well   documented. however, the efficacy of estrogen treatment on bone healing is not well investigated. the drug can be delivered both systemically or locally to the bone with differences in concentrations and side effects. the aim of this study was to investigate the effect of local an...

to evaluate the effectiveness of conjugated estrogen (premarin) and progesterone in twenty-one postmenopausal women who had been menopause one year, we tested during a 6-month period the serum lipoprotein levels in subjects who offered by premarin in dosage of 0.625 milligram for days 1 to 25 and oral medroxy progestrone acetste for days 15 to 25 of a 30-day cycle. twenty-one subjects completed...

Breast cancer remains one of the most frequent malignancies in women and primary cause cancer-related death all over world. Hormones tumor biomarkers have been implicated as possible causes prognostic breast cancer. The present study investigated use serum hormonal levels biomarkers; Carcinoembrvonic antigen (CEA), (CA 15-3) for diagnosis Cancer, generation different subtypes using Estrogen rec...

Substitution at codon Ser315 of katG gene, a reliable marker for isoniazid (INH) resistance and proliferate in spite of the loss of cell wall is called an L- form. Unstable L- forms  can convert to normal cells but stble L-forms can not.cell wall - deffective state may be induced spontaneously or through the action of an appropriate agent such as antibiotic interfering with the synthesis of cel...

Pancreatic ductal adenocarcinoma (PDAC) has a very poor prognosis. A major hurdle to the efficacy of current systemic therapies is abundance non-tumor cells and material, known collectively as stroma, which may both hamper drug delivery support tumor growth resistance. However, restraining activities have also been attributed stroma explain disappointing results stroma-targeting in clinical stu...

OBJECTIVES To assess the usefulness, relative ease of administration, and patient acceptance of the clock drawing test as well as the time and change test for detecting dementia in Chinese elderly adults. DESIGN Prospective case-controlled study. SETTING Memory clinic and geriatric clinic of a district hospital, Hong Kong. PARTICIPANTS A convenient sample of 85 subjects aged 65 years or o...

normal 0 false false false en-us x-none ar-sa background: considering the presence of squamous epithelial cells and fibroblasts in the tympanic membrane (tm), topical estrogen application may influence the repair of tm perforations. therefore, this study was designed to investigate the healing effect of topical estrogen on chronic tm perforations and improvement in hearing threshold. materials ...

BACKGROUND Because cognitive impairment and frailty share common risk factors (eg, high proinflammatory cytokines), we examined whether poor cognition predicts subsequent risk of frailty in initially nonfrail Mexican Americans aged 67 years and older. METHODS Frailty was defined as meeting one or more of the following components: (a) unintentional weight loss of >10 pounds, (b) weakness, (c) ...

See related article, p 1539 In this issue of Stroke, Zamboni et al reported the results of a study that explored whether early cognitive impairment was associated with the volume of white matter hyperintensities and with white matter damage on diffusion-weighted magnetic resonance imaging in patients with transient ischemic attack (TIA) or minor stroke. Cognitive evaluation was performed with t...