OBJECTIVES: Ibuprofen is a non-selective anti-inflammatory cyclooxygenase inhibitor drug of the propionic acid class of non-steroidal agents, available without prescription in the USA. In preterm infants, ibuprofen is used to close the Patent Ductus Arteriosus and it was found to be more effective than indomethacin. This metaanalysis determined whether differences exist in the closure rate of P...

BACKGROUND Genomewide association studies have identified novel genetic factors that contribute to intracranial aneurysm (IA) susceptibility. We sought to confirm previously reported loci, to identify novel risk factors, and to evaluate the contribution of these factors to familial and sporadic IA. METHOD We utilized 2 complementary samples, one recruited on the basis of a dense family histor...

Background : Burn injury is a trauma with high morbidity and mortality that requires special management from the start. stem cells have generated great hopes for treatment of numerous conditions including burns. The Metaanalysis was performed these preclinical studies to assess efficacy possible mechanisms Amniotic Membrane Mesenchymal Stem Cell (AM-MSC) in treating burn wounds.Methods: . Seven...

The current study systematically reviews the literature describing patient outcomes after revision total hip arthroplasties using conventional global hip score ratings. Two thousand one hundred thirty-seven English-language articles published from 1966 through 2000 were identified through a computerized literature search and bibliography review. A three-step filter process was used to identify ...

BACKGROUND Conventional tests are not always helpful in making a diagnosis of tuberculous pleurisy. Many studies have investigated the usefulness of interferon (IFN)-gamma measurements in pleural fluid for the early diagnosis of tuberculous pleurisy. We conducted a metaanalysis to determine the accuracy of IFN-gamma measurements in the diagnosis of tuberculous pleurisy. METHODS After a system...

BACKGROUND Recurrence and reflux are 2 most important remote complications of lap-paraesophageal hernia (PEH) repair. However, the extent of recurrence remains unknown. We sought to determine the true incidence of recurrence after lap-PEH repair. METHODS A meta-analysis was carried out. PubMed, EMBASE, Cochrane Library, hand search, and personal communication were used to access and appraise ...

OBJECTIVE To evaluate the epidemiological and clinical aspects of the different types of odontomas. STUDY DESIGN A metaanalysis was made of 3065 odontomas obtained from a literature review of 30 articles published in recent years. RESULTS Odontomas show no gender predilection, and are most often diagnosed in the second decade of life. They are preferentially located in the upper maxilla, pa...

This report summarizes the proceedings of the first day of the Metagenomics, Metadata and MetaAnalysis (M3) workshop held at the Intelligent Systems for Molecular Biology 2010 conference. The second day, which was dedicated to the inaugural meeting of the BioSharing initiative is presented in a separate report. The Genomic Standards Consortium (GSC) hosted the first day of this Special Interest...