objectives: ziziphus jujube (jujube) plant has exhibited numerous medicinal and pharmacological properties including antioxidant and anti-inflammatory effects. this study was carried out to investigate its anti-cancer and pro-apoptotic abilities in human cervical and breast cancer cells in vitro. materials and methods: the cervical ov2008 and breast mcf-7 cancer cells were incubated with differ...

female cancer, especially breast and gynecologic cancers are considered multistage disease, highly influenced by risk and protective factors and/or screening preventive modalities. consequences of all these factors result in the trend of change over time.in this comparative study, based on data of national cancer registry of iran 2004 published by iranian ministry of health, age - standard inci...

background cervical cancer is the fourth most common cancer among women worldwide. organized cervical screening and vaccination against human papilloma virus (hpv) have been successful interventions for prevention of invasive cervical cancer (icc). because of cultural and religious considerations, icc has low incidence in iran and many other muslim countries. there is no organized cervical scre...

•Metastatic disease should be considered in cervical cancer patients presenting with eye pain and vision complaints.•Distant metastasis involving less common organ sites, such as the eye, suggest a poor prognosis with short life expectancy.•In cases of cervical cancer metastatic to the eye, radiotherapy may decrease the incidence of retinal detachment and vision loss.

BACKGROUND In light of the poor prognosis for cervical cancer, research continues into the development of innovative and efficacious treatment modalities for this disease. We investigated the role of hepatocyte growth factor activator inhibitor-2 (HAI-2) and evaluated its clinical importance in cervical cancer. PATIENTS AND METHODS HAI-2 expression was examined in cervical cancer specimens (n...

Squamous cell carcinoma antigen (SCCA) has been used for the management of squamous cell carcinoma, especially in order to evaluate therapeutic effects and monitor recurrence. Recent studies have shown that SCCA performs several biological functions and can influence the behavior of cancer cells. It is well known that altered expression of E-cadherin is involved in the process of cancer invasio...

Introduction: Cervical lymph node metastases from papillary thyroid cancer were classified into three categories according to ultrasound: 1) Metastases not visible on ultrasound; 2) met initial criteria for the diagnosis; 3) typical diagnosis. Purpose: To develop ultrasound diagnosis of cervical cancer. Material and methods: We studied groups nodes in patients with The first group consisted 430...

The BRCA1-interacted transcriptional repressor ZBRK1 has been associated with antiangiogenesis, but direct evidence of a tumor suppressor role has been lacking. In this study, we provide evidence of such a role in cervical carcinoma. ZBRK1 levels in cervical tumor cells were significantly lower than in normal cervical epithelial cells. In HeLa cervical cancer cells, enforced expression inhibite...

Metastasis means the dissemination of the cancer cells from one organ to another which is not directly connected to the primary site. Metastasis has a crucial role in the prognosis of cancer patients. A few theories, different types of cell and several molecular pathways have been proposed to explain the mechanism of metastasis. In this work, the related articles in the limited period of time, ...

Corresponding Author: Mohammad Mohammadianpanah, MD Cancer Research Center, Department of Radiation Oncology, Namazi Hospital, 71936 13311 Shiraz, Iran, Tel/Fax: +98-711-647 4320 Email: [email protected], [email protected] Introduction Squamous cell carcinoma of the uterine cervix is a major world health problem for women1. It is highly prevalent in developing countries, where the vast major...