AIMS To determine the cost-effectiveness of buprenorphine maintenance therapy for opiate addiction in the United States, particularly its effect on the HIV epidemic. DESIGN We developed a dynamic model to capture the effects of adding buprenorphine maintenance to the current opiate dependence treatment system. We evaluated incremental costs, including all health-care costs, and incremental ef...

OBJECTIVE Physicians may prescribe buprenorphine for opioid agonist maintenance treatment outside of narcotic treatment programs, but treatment guidelines for patients with co-occurring cocaine and opioid dependence are not available. This study compares effects of buprenorphine and methadone and evaluates the efficacy of combining contingency management with maintenance treatment for patients ...

- Methadone, a synthetic opioid agonist, is commonly used for the treatment of heroin dependence. Depending on how alcohol addiction is defined, rates of alcoholism vary among those attending methadone maintenance treatment (MMT) programmes. Most of the current literature has shown that alcohol consumption increases during medium- or long-term MMT. However, up to now, no data have been reported...

Opiates have provided relief from psychic and physical pain for millennia, but their abuse and control has created an international scourge of addiction, misery, crime, and disease. Furthermore, because opiates are frequently administered intravenously, abusers may suffer from and transmit infections, including HIV, hepatitis B, and hepatitis C. Methadone maintenance remains the most successful...

background : the aim of this study was to compare the difficulty in emotional regulation and traits of borderline personality disorder among addicts undergoing methadone treatment, self-referred addicts, and healthy subjects. methods: the current study was a causal-comparative research. the statistical population of this research included all men referring to substance abuse addiction treatment...