Given that buprenorphine + naloxone is prescribed for opioid-dependent pregnant women, it is important to examine the extent to which it differs from buprenorphine alone, methadone, or methadone-assisted withdrawal on neonatal and maternal outcomes. Summary statistics on maternal and neonatal outcomes were collected from 7 previously published studies examining treatment for opioid-dependent pr...

Question Are levo acetyl methadol (LAAM) and buprenorphine as effective as methadone for substitution treatment of opioid dependence? Participants: 220 people categorised as opioid dependent by DSM-IV; 1 groups similar on demographics and drug use history. Exclusion criteria were medical and psychiatric illness requiring long-term medication, and pregnancy. Interventions: (i) Levo acetyl methad...

Many state Medicaid programs restrict access to buprenorphine, a prescription medication that relieves withdrawal symptoms for people addicted to heroin or other opiates. The reason is that officials fear that the drug is costlier or less safe than other therapies such as methadone. To find out if this is true, we compared spending, the use of services related to drug-use relapses, and mortalit...

BACKGROUND Cocaine dependence among opioid-dependent methadone-maintained individuals is a significant public health problem and is particularly challenging to treat. The neurobiology of this clinically complex population has not been previously assessed using fMRI. METHODS fMRI data from cocaine-dependent, methadone-maintained (CD-MM) patients (n=24), cocaine-dependent (CD) patients (n=20) a...

background : the aim of this study was to compare the difficulty in emotional regulation and traits of borderline personality disorder among addicts undergoing methadone treatment, self-referred addicts, and healthy subjects. methods: the current study was a causal-comparative research. the statistical population of this research included all men referring to substance abuse addiction treatment...

BACKGROUND Methadone Medical Maintenance (MMM) was implemented in 1983 to enable socially rehabilitated methadone patients to be treated in the offices of private physicians rather than in the traditional clinic system. Over a period of 15 years, 158 methadone patients who fulfilled specific criteria within the clinic system entered this program in New York City. Participating patients reported...

introduction: addiction is a habit or behavior that is often hard to quit. it is estimated that 190 million persons are substance users around the world. substance abuse creates tolerance after a while. shortly after taking the drug, a person will not enjoy as the beginning of its use that is why the amount of substance used is gradually increased. the purpose of this study was to find the reas...

AIM To analyze the success of three different treatment modalities for heroin addiction: methadone therapy, hospital therapy without methadone, and therapeutic community. METHODS Ninety heroin addicts from the city of Split, Croatia, were systematically allocated to three groups, with 30 participants each, according to the addiction treatment modality they underwent or treatment that resulted...