Protein arginine methyltransferase (PRMT) 1 is involved in the regulation of various metabolic pathways such as glucose metabolism liver and atrophy skeletal muscle. However, role PRMT1 fat tissues under disease state has not been elucidated to date. In this study, we delineate function protein adipocytes vivo. expression was abundant white adipose (WAT), which induced upon a high-fat diet mice...

The current study prepareded to evaluate histopathological and some physiological parameters changes after treated with Nerium oleander L lead. Thus concentrated on tissue structures in the liver aqueous extract of lead solution. Its caused intense flaws albino mice. After expiration experimental time, blood specimens collecting value Aspartate Transaminase (AST), Alanine (ALT), urea (BUN) crea...

ABSTRACT Introduction: Phosphate (CP) its biosynthesis begins with the kidney. Glycocianine was synthesized from glycocianine, then methylated in liver, and finally formed each tissue. Objective: To study effects of phosphatic acid exercise training. Methods: This paper uses 50 pure male mice, 2 month old, weight at 22 ± 3 g, mice per day, 5 minutes time. After training, dry a towel blow it hai...

nano-silver (agnp) has biological properties which are significant for consumer products, food technology, textiles and medical applications (e.g. wound care products, implantable medical devices, in diagnosis, drug delivery, and imaging). for their antibacterial activity, silver nanoparticles are largely used in various commercially available products. thus, the use of nano-silver is becoming ...

Abstract Adequate nutrition is important for proper growth and metabolism. This even more during gestation when insults to the fetus can negatively impact fetal development with persistent effects into adulthood. Using a sheep model, we have demonstrated that maternal restricted feeding (60% of National Research Council requirements) reduced in offspring muscle fiber cross-sectional area. These...

Placental transfer of radioactive C-digitoxin was investigated in four pregnant women. The concentration of the labeled drug and its metabolic products in the various fetal organs was determined. Less than 1 per cent of the administered glycoside was detected in the fetus as unchanged digitoxin and less than 3.5 per cent as its metabolites. The fetal heart and kidney of 11 to ]2 weeks gestation...

The pharmacokinetics and placental transfer of a single dermal 10.0 mg (10microCi)/kg dose of uniformly phenyl-labeled [14C] methyl parathion (0,0-dimethyl 0-4-nitrophenyl phosphorothioate) were investigated in pregnant Sprague-Dawley rats at 14-18 days of gestation. Three rats were killed at each time interval: 1, 2, 4, 12, 24, 48, 72, and 96 h after dosing. Radioactivity disappeared biexponen...

Background and Objectives: Multiple sclerosis is an inflammatory disease of the central nervous system. This is due to migration of peripherally activated lymphocytes to central nervous system leading to inflammatory lesions. However, liver has an anti-inflammatory microenvironment. Myelin expression in the liver of transgenic mice suppresses inflammatory lesions within central nervous system. ...

Alpha, antitrypsin deficiency is one of the most common metabolic disorders, frequently associated with obstructive lung disease and occasionally with childhood liver cirrhosis. Prenatal diagnosis of this deficiency has been accomplished using a DNA polymorphism detected by the restriction enzyme A vall. A unique haplotype ofDNA fragments is observed in deficient (PI type ZZ) subjects. Diagnosi...