نتایج جستجو برای: micro rna

تعداد نتایج: 363773  

Journal: :Journal of molecular pathology 2022

Bile-duct cancers (BDC) are a group of solid tumors arising from the biliary tree. Despite their classification as rare cancers, incidence BDC is increasing worldwide. Poor prognosis common feature this type cancer and mainly determined by following factors: late diagnosis, lack effective therapeutic approaches, resistance to conventional treatments. In past few years, next-generation sequencin...

Journal: :Nucleic acids research 2004
Anna M Heidenblut Jutta Lüttges Malte Buchholz Christian Heinitz Jeppe Emmersen Kåre Lehmann Nielsen Pat Schreiter Manfred Souquet Sandra Nowacki Ulrike Herbrand Günter Klöppel Wolff Schmiegel Thomas Gress Stephan A Hahn

Large-scale gene expression analyses of microdissected primary tissue are still difficult because generally only a limited amount of mRNA can be obtained from microdissected cells. The introduction of the T7-based RNA amplification technique was an important step to reduce the amount of RNA needed for such analyses. This amplification technique produces amplified antisense RNA (aRNA), which so ...

2007
Zhidong Zhang Raza Ahmad David Paton John B. Bashiruddin

Introduction: There is a need to understand the factors which regulate the pathogenesis and persistence of foot-and-mouth disease virus (FMDV). In this paper, the cytokine mRNA levels in micro-dissected epithelium during the acute stage of FMDV infection in cattle were quantified. Materials and Methods: Epithelia from tongue, coronary band on feet and dorsal soft palate were collected from catt...

Journal: :Journal of Cancer Research and Oncobiology 2018

Journal: :International Journal of Current Research and Review 2021

2014
Spyridon Megremis Styliani Taka Anastasis Oulas Georgios Kotoulas Ioannis Iliopoulos Nikolaos G Papadopoulos

Background Micro-RNAs (miRNAs) are a class of small non-coding RNA molecules that function though post transcriptional regulation of gene expression by a process termed RNA interference (RNAi). RNAi–mediated targeting of viral RNAs is recognized as an antiviral defense mechanism. The epigenetic effect of miRNAs can either be direct, by interfering with virus genome, or indirect, through downreg...

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