نتایج جستجو برای: micronization
تعداد نتایج: 166 فیلتر نتایج به سال:
Simvastatin is a poorly water-soluble drug, and bioavailability from its crystalline form is very low. The purpose of this investigation was to increase the solubility and dissolution rate of simvastatin by the preparation of nanosuspensions with Pluronic F127 and zirconium oxide (ZrO2) beads using a wet-milling technique at the laboratory scale. Prepared nanosuspensions were evaluated for part...
ABSTARCT:Emulsion Solovent Diffusion (EDS) technique combines crystallization and agglomeration directly to generate spherical agglomerates with improved micromeretic properties, thus obviating need for further processing by granulation and agglomeration. The present study was focused on spherical crystallization of an antifungal drug Gresiofulvine (GRV) using above mentioned ESD technique in w...
The effect of formulation parameters on the in vitro release profile of a poorly soluble drug was investigated using rimonabant as model drug. A dissolution test was developed to evaluate the release profile of rimonabant from both 20mg film-coated tablet and capsule dosage forms. The test was applied to compare dissolution profiles of different dosage forms and to evaluate the effect of formul...
Curcumin is coming from the Curcuma longa which gives golden color and have the biological importance. As per the survey it is water insoluble, the poor solubility and wettability of curcumin leads to poor dissolution and hence shows poor bioavailability. The present study is aimed at increasing solubility of drug using solid dispersion technique. The solid binary systems were prepared using di...
| References | Full Text: HTML, PDF (Size: 130K) | Supporting information Save Article Structure and composition changes in the cell wall in relation to texture of shiitake mushrooms (Lentinula edodes) stored in modified atmosphere packaging (p 742-749) Tianjia Jiang, Qiushuang Wang, Shasha Xu, Muhammad Muzammil Jahangir, Tiejin Ying Search in this Title Journal of the Science of Food and Agric...
Full: HTML / PDF (1014K) Supporting Info Select Citation Localized Production of Phytoalexins by Peanut (Arachis hypogaea) Kernels in Response to Invasion by Aspergillus Species Victor S. Sobolev pp 1949 1954; (Article) DOI: 10.1021/jf703595w Abstract Full: HTML / PDF (2503K) Select Citation Curcumin, a Known Phenolic from Curcuma longa, Attenuates the Virulence of Pseudomonas aeruginosa PAO1 i...
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