We present a case of invasive pneumococcal infection in a healthy 10-month-old infant from whom Streptococcus pneumoniae serotype 23F was isolated from the blood and serotype 23B was isolated from the cerebrospinal fluid. Both serotypes were penicillin nonsusceptible. Pulsed-field gel electrophoresis analysis demonstrated that the two serotypes had distinct DNA patterns, indicating that infecti...

endothelial cells present in brain are unique and differ from other peripheral tissues in a number of ways, which ensures specific brain endothelial barrier properties. endothelial dysfunction is the earliest event in the initiation of vascular damage caused by inflammation. various micrornas (mirna) have been discovered in different cellular components of the blood bran barrier (bbb). mirnas a...

micrornas are highly conserved small non-coding regulatory rnas that involve in post transcriptional regulating of gene expression during different cellular mechanisms. aberration of mir-218 expression during tumorigenesis of different solid tumors has been reported by numerous studies. in current systematic review article, by using the terms “mir-218” and “cancer” we first searched for english...

Glioma is the most frequent primary intracranial tumor worldwide. Dexmedetomidine an efficient anesthetic used in surgery and has impact on glioma. Yet, mechanism of dexmedetomidine biological characteristics glioma cells unknown. Circ_BRAF, microRNA-381-3p thrombospondin 2 was detected via quantitative reverse transcription-polymer chine reaction. Proliferation detection conducted using 3-(4,5...

*To whom correspondence should be addressed: Rajvir Dahiya, Ph.D. Professor and Director, Urology Research Center (112F), V A Medical Center and UCSF, 4150 Clement Street, San Francisco, CA 94121. Phone: 415-750-6964; Fax: 415-750-6639 E-mail: [email protected]. Running title: miR-23b in prostate cancer. Conflict of Interest: The authors disclose no potential conflicts of interest. Word ...

1Graduate Program in Computational Modeling, Federal University of Juiz de Fora, 36036-330 Juiz de Fora, MG, Brazil 2Department of Applied Physics, Polytechnic University of Catalonia, Avenida Dr. Marañón 44, 08028 Barcelona, Spain 3School of Mathematical Sciences, Rochester Institute of Technology, 85 Lomb Memorial Drive, Rochester, NY 14623, USA 4Simula Research Laboratory, Martin Linges Vei ...

BACKGROUND Intracranial aneurysms are pathological dilatations of the cerebral artery, while rupture of intracranial aneurysms causes life-threatening subarachnoid hemorrhage. The molecular mechanisms of pathogenesis of intracranial aneurysms are poorly understood. MicroRNAs have fundamental roles in modulating vascular biology and disease. In the present study, we carried out a genome-wide cha...