Mucins are important glycoproteins in the mucociliary transport system of the middle ear and Eustachian tube. Little is known about mucin expression within this system under physiological and pathological conditions. This study demonstrated the expression of MUC5B, MUC5AC, MUC4, and MUC1 in the human Eustachian tube, whereas only MUC5B mucin expression was demonstrated in noninflamed middle ear...

BACKGROUND Silver nanoparticles (Ag NPs) displayed strong activities in anti-bacterial, anti-viral, and anti-fungal studies and were reportedly efficient in treating otitis media. Information on distribution of AgNPs in different compartments of the ear is lacking. OBJECTIVE To detect distribution of Ag NPs in the middle and inner ear and transportation pathways after transtympanic injection....

The annular ligament provides a compliant connection of the stapes to the oval window. To estimate the stiffness characteristics of the annular ligament, human temporal bone measurements were conducted. A force was applied sequentially at several points on the stapes footplate leading to different patterns of displacement with different amounts of translational and rotational components. The sp...

Few epidemiological studies of middle ear disease have been conducted in Aboriginal and Torres Strait Islander populations, yet the disease is common and causes hearing impairment and poorer educational outcomes. The objective of this study is to identify factors associated with abnormal middle ear appearance, a proxy for middle ear disease. Aboriginal and Torres Strait Islander children aged 0...

The purpose of this study was to compare CT and radiography for diagnosing the presence and severity of middle ear disease in dogs with chronic otitis externa. Thirty-one dogs that were presented for a total ear canal ablation and bulla osteotomy were recruited. Three normal dogs served as controls. All dogs were examined using radiography and CT. Three radiologists independently evaluated imag...

Bone conduction describes the mechanisms that produce a hearing sensation when the skull bones are subjected to vibration. Multiple components and pathways have been suggested to contribute to total bone-conducted sound. They include outer-ear cartilaginous wall compression, middle-ear inertia, fluid inertia, cochlear capsule compression and soft-tissue conduction. Due to the complexity of the ...

BACKGROUND Ventilation tube insertion is a common treatment for children with persistent otitis media with effusion. Parents are concerned about the morbidity of this procedure and the influence of ventilation tubes on daily activities. Permissibility of swimming is a question that is most often asked. The aim of this study was to investigate the possibility of water penetration through ventila...

Carcinoma of the middle ear and mastoid is a rare condition. The proportion of this disease to all other pathological conditions of the ear has been reported by Towson and Shofstall' as 1: 5 000 to 1: 7 000; by Mattick and Mattick' as 1: 7 000; by Furstenberg' as 1: 20 000; and by Schall' as 1: 6 000. This report documents my personal experience of 5 cases occurring in South African Bantu. Thes...