نتایج جستجو برای: mild tbi

تعداد نتایج: 123135  

Journal: :CNS & neurological disorders drug targets 2015
Dafin F Muresanu Alexandru V Ciurea Radu M Gorgan Eva Gheorghita Stefan I Florian Horatiu Stan Alin Blaga Nicolai Ianovici Stefan M Iencean Dana Turliuc Horia B Davidescu Cornel Mihalache Felix M Brehar Anca S Mihaescu Dinu C Mardare Aurelian Anghelescu Carmen Chiparus Magdalena Lapadat Viorel Pruna Dumitru Mohan Constantin Costea Daniel Costea Claudiu Palade Narcisa Bucur Jesus Figueroa Anton Alvarez

Traumatic brain injury (TBI) is a leading cause of death and disability for which there is currently no effective drug therapy available. Because drugs targeting a single TBI pathological pathway have failed to show clinical efficacy to date, pleiotropic agents with effects on multiple mechanisms of secondary brain damage could represent an effective option to improve brain recovery and clinica...

2015
Timothy E. Sweeney Arghavan Salles Odette A. Harris David A. Spain Kristan L. Staudenmayer

INTRODUCTION Patients with mild traumatic brain injury (TBI) as defined by an admission Glasgow Coma Score (GCS) of 14-15 often do not require neurosurgical interventions, but which patients will go on to require neurosurgical care has been difficult to predict. We hypothesized that injury patterns would be associated with need for eventual neurosurgical intervention in mild TBI. METHODS The ...

Journal: :Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2009

Journal: :Brain Injury 2021

Introduction Traumatic brain injury (TBI) is amongst the leading causes of morbidity and mortality worldwide. The unprecedented emergence COVID-19 has mandated neurosurgeons to limit viral spread spare hospital resources whilst trying adapt management plans for TBI. We aimed characterize how this affects decision-making on TBI drive strategies cope with future expected waves.Methods Retrospecti...

Introduction: The use of standard rodent model, allows for the understanding of neuronal injury physiopathology and helping development of therapeutic strategies. Because of eliminating technical problems, we designed a modified impactor device with ability to induce different degrees according to kilodyne from very mild to very severe of spinal cord injury (SCI) and traumatic brain injury (TBI...

Journal: :Neurology 2012
Erin D Bigler Jason Karlawish

Neurology 2012;78:1454–1455 Progress in treating acute, critical, and often fatal brain injury has been substantial. Prior to modern emergent medical and neurosurgical care, patients with moderate to severe traumatic brain injury (TBI) often did not survive.1 Now, they do and the result is a growing “silent epidemic.”2 The Centers for Disease Control and Prevention (CDC)’s conservative estimate...

2017
Yong Xiao Yigang Fu Yi Zhou Jianguo Xia Lina Wang Chunhong Hu

BACKGROUND The aim of this study was to investigate the relationship between dynamic changes of cerebral metabolism and degree of trauma in rabbit models of traumatic brain injury (TBI) by using proton magnetic resonance spectroscopy (¹H-MRS). MATERIAL AND METHODS Thirty-five Chinese rabbits were randomly divided into control, mild, moderate, and severe TBI groups. ¹H-MRS was performed 1, 6, an...

Journal: :The Journal of head trauma rehabilitation 2009
Heidi Terrio Lisa A Brenner Brian J Ivins John M Cho Katherine Helmick Karen Schwab Katherine Scally Rick Bretthauer Deborah Warden

OBJECTIVES The objective of this article is to report the proportion of soldiers in a Brigade Combat Team (BCT) with at least 1 clinician-confirmed deployment-acquired traumatic brain injury (TBI) and to describe the nature of sequelae associated with such injuries. PARTICIPANTS Members of an Army unit (n = 3973) that served in Iraq were screened for history of TBI. Those reporting an injury ...

Journal: :The Family Journal 2023

Mild traumatic brain injury (mTBI), with symptoms beyond 3 months, may be more common than previously believed, but is poorly understood. This has resulted in contradictory and confused information for service users, which had an impact on those mTBI their families. qualitative study aimed to improve understanding of the lived experiences families people mTBI, months. It extends a previous stud...

Journal: :Journal of child psychology and psychiatry, and allied disciplines 2009
Tisha J Ornstein Harvey S Levin Shirley Chen Gerri Hanten Linda Ewing-Cobbs Maureen Dennis Marcia Barnes Jeffrey E Max Gordon D Logan Russell Schachar

BACKGROUND Executive control deficits are common sequelae of childhood traumatic brain injury (TBI). The goal of the current study was to assess a specific executive control function, performance monitoring, in children following TBI. METHODS Thirty-one children with mild-moderate TBI, 18 with severe TBI, and 37 control children without TBI, of comparable age and sex, performed the stop signa...

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