Glaucoma is a chronic eye disease that leads to blindness. This disease cannot be cured but we can detect the disease in time. Current tests using intraocular pressure (IOP) measurement are not sensitive enough for population based glaucoma screening. Optic nerve head assessment in retinal fundus images is more promising and superior than current methods. This paper proposes segmentation of opt...

Cancer of unknown primary sites (CUP) is a compilation of various malignant entities--the majority of which behave aggressively and carry poor prognosis. CUP is classified into two different clinicopathological groups: the unfavourable (poor-prognosis) and the favourable (good-prognosis) group. Patients with favourable subsets are treated relevant to the hidden primary tumour chemotherapy regim...

Glaucoma is a chronic eye disease that leads to vision loss. As it cannot be cured, detecting the disease in time is important. This research proposes optic disc and optic cup segmentation using superpixel classification for glaucoma screening. It uses the 2D fundus images. In optic disc segmentation, clustering algorithms are used to classify each superpixel as disc or nondisc. For optic cup s...

This paper introduces model uncertainty into the empirical study on determinants of development aid at regional level. is done by adopting a panel Bayesian averaging approach applied data G5 Sahel countries, spanning period 1980–2018. Our results suggest that among regressors considered, those reflecting terrorist attacks, trade stakes including military expenditure, socioeconomic prospects and...

Background and purpose - Most registry studies regarding highly crosslinked polyethylene (XLPE) have focused on the overall revision risk. We compared the risk of cup and/or liner revision for specific cup and liner designs made of either XLPE or conventional polyethylene (CPE), regarding revision for any reason and revision due to aseptic loosening and/or osteolysis. Patients and methods - Usi...

BACKGROUND There are multiple revision implant systems currently available for socket revision in revision total hip arthroplasty. Up until now, not all of these systems have been followed up with regards to their long-term use as a revision implantation.For the first time, this study presents the hemispherical porous-coated socket Plasmacup SC, produced by Aesculap, Tuttlingen, Germany, and th...

Captive-born male and female squirrel monkeys spontaneously 'invented' a cup tool use technique to Contain (i.e., hold and control) food they reduced into fragments for consumption and to Contain water collected from a valve to drink. Food cup use was observed more frequently than water cup use. Observations indicate that 68% (n = 39/57) of monkeys in this population used a cup (a plastic slip ...

BACKGROUND Medialization of the cup with a respective increase in femoral offset has been proposed in THA to increase abductor moment arms. Insofar as there are potential disadvantages to cup medialization, it is important to ascertain whether the purported biomechanical benefits of cup medialization are large enough to warrant the downsides; to date, studies regarding this question have disagr...

Background: Dislocation after total hip arthroplasty is a common complication and partially based on impingement. Questions/purposes: (1) The purpose of this study was to investigate the angle between anterior and posterior impingement in current hip cup designs. (2) Furthermore, the aim was to design a model of an acetabular cup with sparing gaps that match to impact areas. Methods: The range ...

CUP is an eIF4E-binding protein (4E-BP) that represses the expression of specific maternal mRNAs prior to their posterior localization. Here, we show that CUP employs multiple mechanisms to repress the expression of target mRNAs. In addition to inducing translational repression, CUP maintains mRNA targets in a repressed state by promoting their deadenylation and protects deadenylated mRNAs from...