Piper betle L. has traditionally been used in alternative medicine in different countries for various therapeutic purposes, including as an anti-infective agent. However, studies reported in the literature are mainly on its activities on drug susceptible bacterial strains. This study determined the antimicrobial activities of its ethanol, methanol, and supercritical CO2 extracts on clinical iso...

The genus Enterococcus is represented by some of the clinically important species and is well known for its antibiotic resistance, which participates in colonization and infection. Increasing resistance of enterococci has been evoked due to the excessive use of antibiotics not merely for therapeutic purposes or in indicated cases. One of the promising possibilities how to reduce the use of grea...

Tuberculosis is the leading cause of death among the infectious diseases owing to the failure of the present to control the epidemics of the disease. Search for new chemical entities remains the desperate need to control this global scourge. Recently dihydrofusarubin has been reported to exhibit antimicrobial potential. The present study was designed to evaluate the anti-mycobacterial activity ...

Multidrug-resistant bacteria continue to pose the greatest threat public health. Metallic nanoparticles are one of more promising strategies for combating antibiotic resistance. This research aims determine effect gold and silver gold-silver alloy as antibacterial agents. On other hand, biogenic synthesized using Ziziphus spina-christi leaf extract preparation treatment multidrug-resistant were...

Bactericidal testing historically has exhibited variable reproducibility, even when prior standardized methods were employed. Several modifications to the National Committee for Clinical Laboratory Standards (NCCLS) broth macrodilution method are proposed to improve reproducibility. Recommended changes from the approved NCCLS guidelines (M21-A and M26-A) include omitting serum supplementation o...

this study has been done to survey of solvent system effect on extraction of grape seed extract and its antimicrobial properties. for this purpose, grape seed extracts were extracted with six different solvent systems. minimum bactericidal concentration (mbc) of extract on six spoilage and food-born pathogens was determined. the results indicated that mbc of different extracts have no significa...

The antibacterial activities of the essential oil of Eucalyptus globulus (EOEG) was determined against 7 fish pathogenic bacteria (Edwardsiella tarda, Streptococcus iniae, S. parauberis, Lactococcus garviae, Vibrio harveyi, V. ichthyoenteri and Photobacterium damselae) obtained from farmed olive flounder. The inhibitory activity was evaluated by three methods: Disc diffusion method, minimum inh...

The present investigations were aimed to evaluate the antimicrobial and antioxidant efficacies of budmunchiamine-A (BUA) of Albizia amara . The activity-guided isolation leaded to isolate the bioactive compound budmunchiamine-A from alkaloid extract of A. amara . The budmunchiamine-A showed significant broad-spectrum antimicrobial activity with zone of inhibition (ZOI), minimum inhibitory conce...

Gentamicin is a bactericidal aminoglycoside antibiotic, it inhibits the protein synthesis. Gentamicin is active against the majority of aerobic gram-negative bacilli such as Pseudomonas, Klebsiella and Escherichia coli. The gentamicin doses are 3 mg/kg once-daily for preterm newborns < 35 weeks of gestation and 4 mg/kg once-daily for newborns > 35 weeks of gestation. The monitoring of gentamici...