BACKGROUND/AIMS Up to 70% of hemodialysis patients over the age of 54 have relevant cognitive impairment. No standardized protocol for the evaluation and monitoring of this population is available today. We hypothesized that the dialysis procedure and the testing environment induce fluctuations of cognitive performance. METHODS 26 hemodialysis patients were randomly tested using the Montreal ...

Background: We have previously shown that when asthmatics go supine, fluid shifts out of the legs, accumulates in the thorax, and exacerbates lower airway narrowing. In the retrospective analysis of our previous work presented here, we test the hypothesis that the sensitivity of this process relates inversely to baseline caliber of the lower airways. Methods: Eighteen healthy (six women) and si...

We recently engineered encodable lanthanide binding tags (LBTs) into proteins and demonstrated their applicability in Nuclear Magnetic Resonance (NMR) spectroscopy, X-ray crystallography and luminescence studies. Here, we engineered two-loop-LBTs into the model protein interleukin-1β (IL1β) and measured (1)H, (15)N-pseudocontact shifts (PCSs) by NMR spectroscopy. We determined the Δχ-tensors as...

The tumescent technique, developed by dermatologists, has revolutionized the approach to liposuction. It has eliminated concerns about blood loss, fluid replacement and fluid shifts, and the risks and morbidity of general anesthesia. It has also significantly decreased the cost of liposuction by eliminating the need for general anesthesia, an anesthesiologist, a hospital or outpatient operating...

This study aimed to evaluate the effects of an intervention on objective working-hour characteristics. The intervention involved making modifications to the collective agreement that would limit employees' entitlement to time off as compensation. The intervention group consisted of 493 and the control group of 2,303 health and social care shift workers, respectively. We analysed the objective p...

Pollinator shifts are considered to drive floral trait evolution, yet little is still known about the modifications of petal epidermal surface at a biogeographic region scale. Here we investigated how independent shifts from insects to passerine birds in the Macaronesian Islands consistently modified this floral trait (i.e. absence of papillate cells). Using current phylogenies and extensive ev...

The mixed control chart is proposed to improve detection performance with fewer process shifts. In this study, we the modified exponentially weighted moving average - (MMEM), a new for observing changes in mean. Average run length, standard deviation of and median length can be used examine effectiveness detecting Shewhart, Moving (MA), Modified Exponentially Weighted (MEWMA), Mixed (MMME) char...

8 † The 1st (Obolski U) and the 2nd (Lewin-Epstein O) authors contributed equally to this work 9 10 11 Running head: Cooperation accelerates adaptive peak shifts. Abstract 22 Natural selection favors changes that lead to genotypes possessing high fitness. A 23 conflict arises when several mutations are required for adaptation, but each 24 mutation is separately deleterious. The process of a pop...

This paper is concerned with an employee scheduling problem involving multiple shifts and work centers, where employees belong to a hierarchy of categories having downward substitutability. An employee at a higher category may perform the duties of an employee at a lower category, but not vice versa. However, a higher category employee receives a higher compensation than a lower category employ...