JUST over one hundred years ago Robert Graves, in an address to medical students, wrote these words: "Be assured of this, that however accurate be your knowledge of anatomy, however skilful you may be in chemical theories and manipulations, however extensively you may have mastered botany, however well you are acquainted with the nature and properties of drugs-be assured, I say, that you have a...

In this paper, we focus on a “local property” of permutations: value-peak. A permutation σ has a value-peak σ(i) if σ(i − 1) < σ(i) > σ(i + 1) for some i ∈ [2, n − 1]. Define V P (σ) as the set of value-peaks of the permutation σ. For any S ⊆ [3, n], define V Pn(S) such that V P (σ) = S. Let Pn = {S | V Pn(S) 6= ∅}. we make the set Pn into a poset Pn by defining S T if S ⊆ T as sets. We prove t...

The feedback from architectural decisions to the elaboration of requirements is an established concept in the software engineering community. However, pinpointing the nature of this feedback in a precise way is a largely open problem. Often, the feedback is generically characterized as additional qualities that might be affected by an architect’s choice. This paper provides a practical perspect...

Ion-exclusion chromatography (IEC) finds applications in various different analytical separations of weak acids. Pure, deionized water or a diluted, aqueous solution of a strong mineral acid (such as, e.g., sulphuric acid) is used as the mobile phase, whereas a typical stationary phase is a strongly acidic resin in the H(+) form (e.g., the sulfonated polystyrene-divinylbenzene resin with a high...

Abstract The aim of this two-part paper is to investigate the stability properties a special class solutions coagulation-fragmentation equation. We assume that coagulation kernel close diagonal kernel, and fragmentation diagonal. In companion we constructed two-parameter family stationary concentrated in Dirac masses, carefully studied asymptotic decay tails these solutions, showing behaviour s...

The present study describes the development of a comprehensive science and risk based UPLC method and subsequent validation for the simultaneous analysis of related substances of omeprazole and domperidone active pharmaceutical ingredient (API) using a quality by design approach. An efficient experimental design based on systemat ic scuti ng of all three components of the UPLC method (column te...

The real-time ECG signal processing system based on mobile phones is very effective in identifying continuous ambulatory patients. It could monitor cardiovascular patients in their daily life and warns them in case of cardiac arrhythmia. An ECG signal of a patient is processed by a mobile phone with this proposed algorithm. An IIR low-pass filter is used to remove the noise and it has the 55 Hz...

The low-energy electronic excitations in cobalt are studied by a theoretical method that includes many-body effects and a realistic description of the band structure. Angle-resolved photoemission spectra measured on a thick film of hexagonal close-packed Co on Cu(111) agree well with calculated spectral functions. Because of many-body effects no sharp quasiparticle peaks exist for binding energ...