Department of Microbiology and Molecular Genetics, Harvard Medical School and New England Primate Research Center, Southborough, Massachusetts; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Laboratory of Molecular Medicine, Children’s Hospital, Boston, Massachusetts; Department of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Berlin, Germany...

A. Scheybal,1 K. Müller,1 R. Bertschinger,1 M. Wahl,2 A. Bendounan,3 P. Aebi,4 and T. A. Jung1 1Laboratory for Microand Nanotechnology, Paul Scherrer Institut, CH-5232 Villigen PSI, Switzerland 2Institut für Physik, Universität Basel, Klingelbergstrasse 82, CH-4056 Basel, Switzerland 3Synchrotron Soleil, L’Orme des Merisiers, Saint-Aubin, BP 48, F-91192 Gif-sur-Yvette Cedex, France 4Institut de...

Computational Thermodynamics and Phase Transformations: First Principles and Atomistic Calculations of Phase and Alloy Thermodynamics II Sponsored by: The Minerals, Metals and Materials Society, ASM International, TMS Electronic, Magnetic, and Photonic Materials Division, TMS Materials Processing and Manufacturing Division, ASM Materials Science Critical Technology Sector, TMS: Chemistry and Ph...

Laboratory-based surveillance, one of the pillars of monitoring infectious disease trends, relies on data produced in clinical and/or public health laboratories. Currently, diagnostic laboratories worldwide submit strains or samples to a relatively small number of reference laboratories for characterisation and typing. However, with the introduction of molecular diagnostic methods and sequencin...

X. Moles Lopez, O. Debeir, I. Salmon and C. Decaestecker 1 DIAPATH, Center for Microscopy and Molecular Imaging, Université Libre de Bruxelles, Rue Adrienne Bolland 8, B6041 Gosselies, Belgium 2 Laboratories of Image, Signal processing and Acoustics, Brussels School of Engineering, Université Libre de Bruxelles, 50, av. Franklin Roosevelt, B-1050 Brussels, Belgium 3 Department of Pathology, Era...

The purpose of this article is to provide the reader with an overview of the methods used to determine the molecular weights of cellulose. Methods that employ direct dissolution of the cellulose polymer are described; hence methods for investigating the molecular weight of cellulose in derivatized states, such as ethers or esters, only form a minor part of this review. Many of the methods descr...

Electroporation (EP) of drugs and genes into cells in vitro became a standard procedure in molecular biology laboratories in the last decade. Numerous protocols aid the researcher in selecting appropriate procedures; commercial instrumentation is readily available and discussed (1). The more recent transition to applying EP to living tissue poses a new set of requirements and few practical guid...

Since 1993, the reporting of listeriosis has been mandatory in Italy. The surveillance system based on case notifications from physicians is managed by the Ministry of Health. The information collected includes only gender, age and case distribution by region. To gather more information, an active surveillance was conducted for 12 months (2002-2003). All hospital microbiological laboratories in...

BACKGROUND A variety of proficiency testing schemes are available for specific molecular analyses, but there is an acute need for more widely accessible schemes to assess and demonstrate general competence in DNA analysis. METHODS Fifteen laboratories, including academic, clinical, and commercial organizations, were recruited into the prototype assessment exercise. A range of test samples wer...