The estimated prevalence of ventilator-dependent individuals in Europe is 6.6 per 100 000 people. The increasing number and costs of these complex patients make present health organisations largely insufficient to face their needs. As a consequence, their burden lays mostly over families. The need to reduce healthcare costs and to increase safety has prompted the development of tele-monitoring ...

BACKGROUND Updated World Health Organization guidelines have amplified debate about how resource constraints should impact monitoring strategies for HIV-infected persons on combination antiretroviral therapy (cART). We estimated the incremental benefit and cost effectiveness of alternative monitoring strategies for east Africans with known HIV infection. METHODS Using a validated HIV computer...

Unscheduled aircraft maintenance causes a lot problems and costs for aircraft operators. This is due to the fact that aircraft cause significant costs if flights have to be delayed or canceled and because spares are not always available at any place and sometimes have to be shipped across the world. Reducing the number of unscheduled maintenance is thus a great costs factor for aircraft operato...

UNLABELLED Monitoring of cyclosporine (microemulsion CsA) at 2 hours post-dose (C2), a measure of absorption and exposure, appears superior to trough (C0) monitoring for prediction of rejection risk. The purpose of this study was to determine whether C2 was cost-effective compared to C0 in Argentina. METHODS A predictive decision model was adapted to Argentina to predict costs associated with...

Since 1986, studies about the escape decisions made by prey are grounded in optimal escape theory (OET) which states that prey will initiate escape when the risk of remaining and the costs of leaving are equal. However, a recent hypothesis, Flush Early and Avoid the Rush (FEAR), acknowledged that the cost of monitoring approaching predators might be a ubiquitous cost. The FEAR hypothesis predic...

Many applications benefit from the ability to monitor the value of conditions over large, possibly distributed data sets. However, mechanisms to achieve this typically impose a performance overhead that the owners and users of such systems may be unwilling to accept. A compromise solution is to allow system owners to decide at what times they will allow computational resources to be given over ...

Microbial water quality monitoring is crucial for managing water resources and protecting public health. However, institutional testing activities in sub-Saharan Africa are currently limited. Because the economics of water quality testing are poorly understood, the extent to which cost may be a barrier to monitoring in different settings is unclear. This study used cost data from 18 African mon...

This article discusses the limits of the transaction cost explanation of the existence of the firm. It develops three simple models that compare the profitability of firms and markets, two without transaction costs related to market trading. In both firms and markets it is assumed that skills increase due to a static specialisation effect. In addition, in the first two models, firms benefit fro...