A method for rapid morphologic phenotyping is demonstrated by using magnetic resonance microscopy. Whole fixed C57BL/6J mice were imaged at 110-microm isotropic resolution; limited volumes of the intact specimen, at 50-microm isotropic resolution; and isolated organs, at 25-microm isotropic resolution. The three-dimensional imaging technique was applied to uricase knockout mice to demonstrate t...

The authors analyze experimental intoxication manifestations under the effects of chemical compounds of different classes using various morphologic methods including cytospectrophotometric analysis of the activities of a number of redox and hydrolytic enzymes. Types of structural and metabolic restructuring of the elements and microcirculatory bed of some organs during their toxic injury are de...

Zoltan Alexin Department of Informatics University of Szeged [email protected]—szeged.hu Tibor Gyinnithy Research Group on Artifical Intelligence at University of Szeged [email protected]—szeged.hu Csaba Hatvani Department of Informatics University of Szeged [email protected]—szeged.hu LaszlO Tihanyi MorphoLogic Budapest [email protected] Janos Csirik Department of Informatics University of Szeged csiri...

Consideration of newer more quantitative morphologic approaches to the study of aquatic pollutants can provide opportunity for collaborative/integrated studies with other subdisciplines in toxicology. Current commonly employed morphologic approaches result largely in subjective findings difficult to analyze statistically and often are directed at levels of structural organization inconsistent w...

I N SPITE of the rarity of eosinophilic leukemia, many investigators have reported a number of morphologic alterations of the eos nophils present in the blood and/or bone marrow of patients with eosinophilic leukemia.6’1 ‘ 13.1 6, 18, 19,21 ,24,26,293 I ,34,36,39,40,42,45,4753 The cytologic alterations have included a sparcity of eosinophilic granulation in the mature eosinophils, asynchronous ...

The morphologic consequences of transluminal angioplasty of stenotic atherosclerotic coronary arteries are unknown. This study describes the production of aortoiliac atherosclerosis in rabbits and reports the morphologic changes after transluminal angioplasty of stenotic arterial lesions. Atherosclerotic lesions were evaluated angiographically before and after transluminal angioplasty and were ...

Flow cytometric analyses of cellular DNA, RNA, and double-stranded RNA content were performed on lymph nodes and extranodal tissue from 177 patients with non-Hodgkin's lymphoma. With increasing histologic grade, a higher incidence of aneuploidy, higher proliferative activity, and higher total and double-stranded RNA content were found. Despite considerable cytometric heterogeneity within histol...

In the paper, preliminary results for the classification of microcalcifications (MCs) into the three BIRADSTM morphologic categories (punctate, pleomorphic and linear) have been presented. To classify the microcalcifications into morphologic types the set of 27 shape descriptors has been constructed. The morphology of the cluster has been determined as the mean values of shape descriptors for s...

We evaluated the role of flow cytometric immunophenotyping (FCI) in the assessment of bone marrow (BM) specimens in 104 patients with mantle cell lymphoma (MCL) following treatment with aggressive combination chemotherapy. Of the patients, 77 had no morphologic or FCI evidence of MCL, 13 had morphologic and FCI evidence of MCL, and 14 patients were morphologically negative but FCI showed CD5+ c...

Erythema gyratum repens (EGR) is a rare, inflammatory dermatosis of unknown aetiology. The morphology of the eruption is striking and displays rapidly evolving circinate and gyrate bands of erythematous and scaly skin. Although the aetiology of the pattern is unknown, it has previously been noted that the eruption shares morphologic features with the patterns of spatio-temporal chemical concent...