the human erythrocyte is a rich raw material for the purification of cu-zn superoxide dismutase (sod). we applied a simple and rapid procedure for the purification of sod from human erythrocytes by ion exchange chromatography. the purified sod had a specific activity of 2285.6 u/mg protein and gave a single band on polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate (sd...

in vitro antioxidant and erythrocyte protecting activities by aqueous extract of ficus thonningii leaves on blood cells were studied in acetaminophen treated rats. the extract was safe at limit dose of 5000 mg kg-1body weight. the extract demonstrated dose dependent antihemolytic effect at dose levels between 50 and 200 mg kg-1 body weight. the lowest antihemolytic effect was observed at dose l...

Background: We intend to study the inhibitory effect of sulfur compound in Ramsar hot spring mineral on tumor-genesis ability of high natural background radiation. Objective: The radioprotective effect of sulfur compounds was previously shown on radiation-induced chromosomal aberration, micronuclei in mouse bone marrow cells and human peripheral lymphocyte. Ramsar is known for having the highe...

Chronic ethanol consumption leads to oxidative stress in the heart and erythrocytes of rats. As Ziziphus jujuba fruit has been shown to have potent antioxidants, such as flavonoids, we conducted this study to evaluate the effects of aqueous fruit extracts from Z. jujuba on rat hearts and erythrocytes following chronic ethanol consumption. Twenty-eight male Wistar rats were randomly divided into...

Previous research has shown that glycolytic enzymes (GEs) exist as multi-enzyme complexes on the inner surface of human erythrocyte membranes. Because GE binding sites have been mapped to sequences on the membrane protein, band 3, that are not conserved in other mammalian homologs, the question arose whether GEs can organize into complexes on other mammalian erythrocyte membranes. To address th...

purpose: deformability/rheologic behavior of erythrocytes are related to near-surface membrane fluidity. specific agents can increase erythrocyte membrane fluidity in order to adjust hemodynamics in cardiovascular diseases. grapefruit flavanone naringenin has been proposed for potential use in an alternative therapy of cardiovascular conditions. in respect to this, we assessed here effects o...

the effect of long-term onion consumption on red blood cell antioxidant enzymes [glucose-6-phosphate dehydrogenase (g6pd), superoxide dismutase (sod) and glutathione peroxidase (gpx)], were measured. the relationship of these enzymes with pcv and hemoglobin (hb) concentrations was also determined. twelve adult female goats were used for the experiment and randomly assigned to three groups. anim...