The ERNDIM Urine Mucopolysaccharide scheme is aiming at (1) provision of urine samples obtained from confirmed MPS patients to enable laboratories to gain or maintain experience to identify MPS patients and (2) proficiency testing of laboratories providing urine screening of mucopolysaccharidosis. The scheme is organised by Erasmus Medical Centre (Rotterdam, NL) in conjunction with SKML, the Du...

PULMONARY EDEMA FLUID is not just water but is instead a complex biological medium. The daedal nature and variability of its makeup are particularly apparent when samples of alveolar edema or bronchoalveolar lavage fluid from patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are examined compared with those from subjects with hydrostatic (“cardiogenic”) pulmonary ...

We present a new response-time analyzer for Controller Area Network (CAN) that integrates and implements a number of response-time analyses which address various transmission modes and practical limitations in the CAN controllers. The existing tools for the response-time analysis of CAN support only periodic and sporadic messages. They do not analyze mixed messages which are partly periodic and...

BACKGROUND Microparticles (MPs) are released from the plasma membrane of activated or dying cells and bear surface molecules from those cells. We examined whether donor-derived MPs in the peripheral blood of the recipient could serve as a marker of tissue damage due to rejection of a transplanted hand. METHODS Platelet-free plasma from the recipient of the transplanted hand was analyzed for M...

The effect of the Shwartzman phenomenon on the metabolism of the acid mucopolysaccharides (MPS), hyaluronic acid and chondroitin sulfate, from rabbits with localized lesions was studied. Quantitative changes of MPS were observed by two techniques-the in vivo incorporation of glucose C(14) into the MPS and the in vitro dilution of C(14)-labeled MPS. The results indicate an increased concentratio...

This study included 18 cases with hepatomegaly referred to the Human Genetics Department, National Research Centre with a suspicion of a metabolic disorder from 2006 to 2008. The aim of our study was to find out the importance of hepatomegaly as sign for many metabolic disorders and their frequency among other disorders with hepatomegaly. All cases were subjected to clinical and biochemical stu...

The mechanisms of action of mineral phosphate solubilization (MPS) were studied in the wild-type Mps‡ Penicillium rugulosum strain IR94-MF1 and in negative (Mps3) and superpositive (Mps‡‡) mutants derived from it. MPS activities were measured in liquid media using sucrose as C source, four N (arginine, nitrate, nitrate+ammonium and ammonium) and P sources (KH2PO4, hydroxyapatite, FePO4 and AlPO...

The maximum product of spacings (MPS) is employed in the estimation of the Generalized Extreme Value Distribution (GEV) and the Generalized Pareto Distribution (GPD). Efficient estimators are obtained by the MPS for all γ. This outperforms the maximum likelihood method which is only valid for γ < 1. It is then shown that the MPS gives estimators closer to the true parameters compared to the max...

Microparticles (MPs) are increasingly recognized as important mediators of cell-cell communication in tumour growth and metastasis by facilitating angiogenesis-related processes. While the effects of the MPs on recipient cells are usually well described in the literature, the leading process remains unclear. Here we isolated MPs from ovarian cancer cells and investigated their effect on endothe...

Revising the master production schedule (MPS) in a rolling planning horizon environment to improve plant performance is critical in process industries with sequence dependent changeovers. Plant performance is defined in terms of process changeover time, total shortages, and finished goods inventory. Two heuristics for revising the MPS are introduced and tested against a rolling horizon MPS that...