BACKGROUND Helminth infections in animals to be consumed by humans are an important medical and public health problem. Pharmaceutical research has focused on developing new anthelmintic drugs for parasite control these animals. However, the incorrect use of anthelmintics can leave residues animal products intended human consumption. Their determination is therefore crucial terms food safety. RE...

Background: The presence of pollutants in honey can influence honey bee colony performance and devalue its use for human consumption. Using liquid chromatography tandem mass spectrometry (LC-MS/MS), various clean-up methods were evaluated for efficient determination of multiclass pesticide contaminants in honey. The selected clean-up method was optimized and validated and then applied to perfor...

This application note describes the use of a quick, easy, cheap, effective, rugged, and safe (QuEChERS) AOAC sample preparation approach for extraction and cleanup of 18 GC-amenable multiple pesticide class residues in spinach. The method employed involves initial extraction in a buffered aqueous/acetonitrile system, an extraction/ partitioning step after the addition of salt, and a cleanup ste...

This application note describes a method for the quantitative determination of 26 mycotoxins in sesame butter based on the work published by Liu et al. [1]. The sample was initially extracted and cleaned up using a modified QuEChERS protocol developed in the lab, and the resultant solution was subjected to separation and detection using an Agilent 1290 Infinity LC System coupled to an Agilent 6...

An amperometric magneto-immunosensor (AMIS) for the detection of residues of fluoroquinolone antibiotics in milk samples is described for the first time. The immunosensor presented combines magnetic beads biomodified with an antibody with a broad recognition profile of fluoroquinolones, a haptenized enzyme and a magnetic graphite-epoxy composite (m-GEC) electrode. After the immunochemical react...

During 3 years of a monitoring programme, 522 samples of fresh apples, six brands of fruit purées and various types of fruit baby food prepared from these materials were analysed. Each sample was examined for the presence of 86 GC amenable pesticide residues. The reporting limits of the procedure employed for sample analyses were in the range 0.003-0.01 mg kg(-1). Pesticide residues were detect...

To conduct exposure-based assessments of possible noncancer or cancer health hazards from oral exposures to mixtures of 2,3,7,8-TCDD, hexachlorobenzene, p,p’-DDE, methylmercury, and PCBs, component-based approaches are recommended, because there are no direct data available to characterize health hazards (and dose-response relationships) from exposure to the mixture. In addition, PBPK/PD models...

Residues of benzoylphenylurea insecticides (diflubenzuron, hexaflumuron, and flufenuxuron), carboxamide acaricides (hexythiazox), and carbamate insecticides (benfuracarb) were determined in 150 orange fruit samples from September 1998 to June 1999, to estimate exposure of the Valencian population to oranges contaminated with these newly developed pesticides. The method for monitoring these resi...

Background: Tetracycline antibiotics are widely used for prevention and control of disease. However, the presence of tetracycline antibiotics residues in food is a serious public health concern because of the harmful effects of these residues on consumer's health. Therefore, it is necessary to detect tetracycline residues in food of animal origin keeping in view the food safety issues and probl...

This paper presents the validation of a modified QuEChERS method in four matrices - green tea, red tea, black tea and chamomile. The experiments were carried out using blank samples spiked with a solution of 86 pesticides (insecticides, fungicides and herbicides) at four levels - 10, 25, 50 and 100 μg/kg. The samples were extracted according to the citrate QuEChERS protocol; however, to reduce ...