Neonatal administration of MSG leads to a syndrome of endocrine dysfunction characterised by reduced growth, obesity and hypogonadism. The aim of the present investigation was to gain information on the structure and function of the pituitary-thyroid axis in MSG-treated rats. Neonatal Wistar rats received an s.c. MSG (4 mg/g body weight) or hyperosmotic saline (controls) on days 2, 4, 6, 8 and ...

Monosodium glutamate (MSG) was given to neonatal male rats to determine its effects on neurons containing beta-endorphin (beta-END) and alpha-melanocyte stimulating hormone (alpha-MSH) within the basal hypothalamus (arcuate nucleus) and caudal medulla [nucleus tractus solitarius (NTS)] and on the levels of beta-END and alpha-MSH within these areas. Immunocytochemical studies demonstrated a redu...

Electrochemical biosensors are widely investigated as they represent attractive analytical tools for detection of a broad range bio-molecules, thanks to their simplicity, high sensitivity and short response time. Especially, employing an electrolyte-gated field-effect transistors (EG-FETs) electrochemical transduction element have gained increasing interest, due the signal amplification intrins...

The effects of Monosodium glutamate (MSG), a popular food additive, on hematopoietic and cardiovascular risk variables in animal have not been reported till date. We report here the effects of MSG on the said variables in rat model. Adult female rats of Charles foster strain weighing about 100-120 gms were administrated MSG at a dose level of 0.8gm/kg/day, 1.6gm/kg/day, 2.4gm/kg/day, respective...

Monosodium glutamate (MSG) has been recognized as flavor enhancer that adversely affects male reproductive systems. The present study was carried out to evaluate the potential protective role of vitamin E (vit E) or selenium against MSG induced oxidative stress and histopathological changes in testis tissues of rats. Mature male Wistar rats weighing 150-200 g BW were allocated to evenly twelve ...

Whole nerve, as well as single fiber, responses in the chorda tympani proper (CT) and glossopharyngeal (NG) nerves of 1- to 7-week-old pigs were recorded during taste stimulation. In the CT acids and in the NG bitter compounds gave the largest responses. Both nerves exhibited large responses to monosodium glutamate (MSG), MSG with guanosine 5'-monophosphate (GMP) and MSG with inositine 5'-monop...

In this study, the performance of the modified subgradient algorithm (MSG) to solve the 0-1 quadratic knapsack problem (QKP) is examined. The MSG is proposed by Gasimov for solving dual problems constructed with respect to sharp Augmented Lagrangian function. The MSG has some important proven properties. For example, it is convergent, and it guarantees the zero duality gap for the problems such...

BACKGROUND Fibromyalgia is a common rheumatologic disorder that is often difficult to treat effectively. CASE SUMMARY Four patients diagnosed with fibromyalgia syndrome for two to 17 years are described. All had undergone multiple treatment modalities with limited success. All had complete, or nearly complete, resolution of their symptoms within months after eliminating monosodium glutamate (...

Glutamate sensors in the oral cavity, gastrointestinal canal and hepatoportal region are thought to function in the reflex regulation of vagal activity to the gastrointestinal tract and pancreas. In support of this notion, the findings summarized in this report demonstrate that the infusion of monosodium glutamate (MSG) into the stomach (150 mmol/L, 3 mL), duodenum (150 mmol/L, 3 mL) and portal...

BACKGROUND Monosodium glutamate (MSG) is a widely-used flavor enhancer and stabilizer in ready-made or packaged foods. The excessive use of MSG has been shown to increase oxidative stress in different organ systems and causes glucose metabolism disorders, obesity, and coronary diseases. OBJECTIVES In this study, the antioxidant activity of tannic acid was investigated experimentally with resp...