Although much work has implicated the contributions of frontostriatal and medial temporal lobe (MTL) systems during probabilistic classification learning, the impact of emotion on these learning circuits is unknown. We used a modified version of the weather prediction task in which two participant groups were scanned with identical neutral cue cards probabilistically linked to either emotional ...

The yeast Candida albicans can mate. However, in the natural environment mating may generate progeny (fusants) fitter than clonal lineages too rarely to render mating biologically significant: C. albicans has never been observed to mate in its natural environment, the human host, and the population structure of the species is largely clonal. It seems incapable of meiosis, and most isolates are ...

Constructing autobiographical events involves an initial phase of event selection, in which a memory or imagined future event is initially brought to mind, followed by a phase of elaboration, in which an individual accesses detailed knowledge specific to the event. While considerable research demonstrates the importance of the medial temporal lobes (MTL) in the later phase, its role in initial ...

Introduction: The human stature forms part of his or her biological profile. It becomes more important during personal identification in case of mass disasters and in search of missing persons. We measured various parameters of the dried tibia, then by applying linear regression we formulated maximum tibia length which can be conveniently used for arriving at human stature. Methods: The obtain...

A multi-task learning (MTL) framework, called gradient kernel ridge regression, for nuclear masses and separation energies is developed by introducing functions to the regression (KRR) approach. By taking WS4 mass model as an example, KRR network trained with residuals, i.e., deviations between experimental theoretical values of one-nucleon energies, improve accuracy predictions. Significant im...

BACKGROUND AND PURPOSE It is not known whether carbamazepine (CBZ; a drug widely used in neurology and psychiatry) influences the blood oxygenation level dependent (BOLD) contrast changes induced by neuronal activation and measured by functional MRI (fMRI). We aimed to investigate the influence of CBZ on memory induced activation of the mesial temporal lobes in patients with symptomatic tempora...

Initial genetic studies in Drosophila suggested that several members of the Rho subfamily (RhoA, Rac1 and Cdc42) are involved in planar cell polarity (PCP) establishment. However, analyses of Rac1, Rac2 and Mtl loss-of-function (LOF) mutants have argued against their role in this process. Here, we investigate in detail the role of the Rho GTPases Mtl, Cdc42, Rac1 and Rac2 in PCP generation. The...

The Microsystems Technology Laboratories (MTL) is an interdepartmental laboratory with a mission to foster research and education in semiconductor process and device technology, and in integrated circuits and systems design. MTL provides microand nanofabrication and computer-aided design (CAD) infrastructure to the entire campus. MTL has 43 core faculty members who are engaged in diverse resear...

Studies of cognitive and neural aging have recently provided evidence of a shift from an early- to late-onset cognitive control strategy, linked with temporally extended activity in the prefrontal cortex (PFC). It has been uncertain, however, whether this age-related shift is unique to PFC and executive control tasks or whether the functional location might vary depending on the particular cogn...

Candida albicans, which is diploid, possesses a single mating-type (MTL) locus on chromosome 5, which is normally heterozygous (a/alpha). To mate, C. albicans must undergo MTL homozygosis to a/a or alpha/alpha. Three possible mechanisms may be used in this process, mitotic recombination, gene conversion, or loss of one chromosome 5 homolog, followed by duplication of the retained homolog. To di...