T ERMATOSES of diverse etiology have been -I-~ reported to give rise to skin and mucous membrane lesions whose morphology, symptomatology, course, and microscopic picture cannot be distinguished from lichen planus. Drugs,1-6 vaccines,7 contact with chemicals,8-'3 and exposure to ultraviolet light and Grenz rays14 are prominent among the causative agents which have been observed to produce liche...

Even though we are all exposed to various pathogens at all times, we only seldom become clinically ill. This is because we are endowed with a robust immune apparatus that is highly evolved and multi-facet with the ability to distinguish between “self” and “non-self”. On escaping and by-passing the mechanical barriers like the skin and muco ciliary clearances, as a part of the antigen non-specif...

1. Xagrid Summary of Product Characteristics, July 2014 2. Hong Y et al. Platelets. 2002 3. Petrides et al. Expert Opin Pharmacother 2004 4. Barosi G, Leukemia. 2007 Feb;21(2):277–80 Non-cytotoxic activity that allows long-term clinical use: no known mutagenic, clastogenic or leukemogenic properties1-3 If, with first-line HU: • The patient does not achieve an adequate response: if the platelet ...

W. McC., age 17 years. This patient attended E.N.T. Extern and was admitted to the Royal Victoria Hospital on the 16th September, 1949. He complained of nasal obstruction for one year which was noticed first on the right side and later on the left. Four months before admission he had a severe epistaxis, during which he lost a considerable amount of blood. He was treated six months previously fo...

Cancer patients, especially stem cell transplantation recipients and patients with leukemia, constitute a high-risk group for the development of life-threatening systemic fungal infections. Candidiasis represents the most commonly reported fungal infection in cancer patients. Candidemia alone is associated with a mortality rate above 50% in this patient population. Even more challenging than th...

The purpose of the present study was to design muco-adhesive chitosan microspheres containing amoxicillin. Chitosan microspheres with a small particle size and good sphericity were prepared by a spray-drying method followed by chemical treatment with a chemical crosslinking agent (glutaraldehyde). Parameters affecting the crosslinking extent of the crosslinking time and the concentration of the...

portion of the chest; on the left side the breathing was peurile ; there was no tenderness on pressure over the hepatic region, but there appeared to be some enlargement of the liver downwards, and towards the left hypochondrium; the sputum was a sanguinolent fluid with greyish white masses of a muco-purulent character floating in it; the quantity varied; some days it was very large, as much as...