Secondary Metabolites of Soil Actinomycetes, UTMC 676 and 919, Induces Apoptosis in Human Non‑Small-Cell Lung Cancer Cell Line

Malic enzyme (ME) is one of the important enzymes for furnishing the cofactor NAD(P)H for the biosynthesis of fatty acids and sterols. Due to the existence of multiple ME isoforms in a range of oleaginous microbes, a molecular basis for the evolutionary relationships amongst the enzymes in oleaginous fungi was investigated using sequence analysis and structural modelling. Evolutionary distance ...

Filamentous fungi are good producers of different extracellular enzymes. Due to this feature, some of them assumed to play an important role in the decomposition of plant and other organic materials. Several members of the class Zygomycetes are involved in different biotechnological applications, in consequence of their efficient extracellular enzyme production. Because of the increasing intere...

The genome of a high lipid-producing fungus Mucor circinelloides WJ11 (36% w/w lipid, cell dry weight, CDW) was sequenced and compared with that of the low lipid-producing strain, CBS 277.49 (15% w/w lipid, CDW), which had been sequenced by Joint Genome Institute. The WJ11 genome assembly size was 35.4 Mb with a G+C content of 39.7%. The general features of WJ11 and CBS 277.49 indicated that th...

The epigenetic modifications control the pathogenicity of human pathogenic fungi, which have been poorly studied in Mucorales, causative agents mucormycosis. This order belongs to a group referred as early-diverging fungi that are characterized by high levels N6-methyldeoxy adenine (6mA) their genome with dense 6mA clusters associated actively expressed genes. AlkB enzymes can act demethylases ...

Abstract The use of eco-friendly methods for the synthesis nanoparticles and its nano-composite has become a public demand nowadays to reduce risks chemical methods. In current study, green Cu-doped ZnO based polymers nan-ocomposite was performed. Various instrumental analysis including UV–vis, ATR-FTIR spectroscopy, XRD, SEM coupled with energy dispersive X-ray analysis, TEM Thermal gravimetri...