Multiagent systems have been touted as a way to meet the need for distributed software systems that must operate in dynamic and complex environments. However, in order for multiagent systems to be effective, they must be reliable and robust. Engineering multiagent systems is a non-trivial task, providing ample opportunity for even experts to make mistakes. Formal transformation systems can prov...

In this paper we introduce and discuss five guidelines for the use of normative systems in computer science. We adopt a multiagent systems perspective, because norms are used to coordinate, organize, guide, regulate or control interaction among distributed autonomous systems. They are derived from the computer science literature. From the so-called ‘normchange’ definition of the first workshop ...

With the growing usage of the world-wide ICT networks, agent technologies and multiagent systems are attracting more and more attention, as they perform well in environments that are not necessarily well-structured and benevolent. Looking at the problem solving capacity of multiagent systems, emergent system behaviour is one of the most interesting phenomena, however, there is more to multiagen...

Non-Hodgkin's lymphoma (NHL) is a very rare complication of acute lymphoblastic leukemia (ALL). We present the pathologic, clinical, immunologic, and ultrastructural features of the third reported example of NHL following successfully treated ALL. This white girl developed ALL with predominantly L1 cells at 3.5 yr of age. The lymphoblasts were terminal deoxynucleotidyl transferase (TdT) positiv...

Osteosarcoma is the most common primary malignancy of bone. It arises in bone during periods of rapid growth and primarily affects adolescents and young adults. The 5-year survival rate for osteosarcoma is 60%-70%, with no significant improvements in prognosis since the advent of multiagent chemotherapy. Diagnosis, staging, and surgical management of osteosarcoma remain focused on our anatomica...

OBJECTIVE To report the clinical characteristics, pathologic findings and treatments of a patient with a Caesarean scar choriocarcinoma. PATIENT HISTORY A 22-year-old woman had a diagnosis of primary gestational choriocarcinoma in a uterine Caesarean scar misdiagnosed as a normal Caesarean scar pregnancy. The patient underwent selective uterine artery embolization coupled with methotrexate ar...

Following improvements in therapy for childhood malignancies, the striking increase in survival rate over the past 30 years has led to the increase risk of developing second malignant neoplasms (SMNs). We report a case of colorectal carcinoma as a SMN, following treatment for rhabdomyosarcoma. The patient was diagnosed with rhabdomyosarcoma of the urinary bladder at his age of three years, and ...