BACKGROUND Differences in circulating concentrations of antiangiogenic factors sFlt1 and soluble endoglin (sEng) and the pro-angiogenic growth factor PlGF are reported to precede the onset of preeclampsia weeks to months in low-risk pregnant women. The objective of this study was to investigate whether similar changes can be detected in pregnant women at high-risk to develop the syndrome. MET...

SummaryBackground Prospective data about the risks of thrombotic and severe haemorrhagic complications during pregnancy post partum are unavailable for women with antiphospholipid syndrome. We aimed to assess events in a prospective cohort pregnant Methods This multicentre, prospective, observational study was done at 76 centres France. To be eligible this study, had ...

Ultrasound plays an increasing role in the evaluation, monitoring, and treatment of infertility. About 15% of all couples attempting to have children are affected by infertility. As women delay conception due to career choices and age, the frequency of infertility increases. Infertility is defined as no conception after one year of unprotected intercourse. Ultrasound plays a remarkable role in ...

Over the past 25 years the rate of twin and higher - order multifetal birth have increased between 1980 and 2005. The twining rate rose from 18.9 to 32.1 per 1000 live birth. Multifetal gestations are at high risk of fetaland complication such as; growth restricted fetal death, LBW and cerebral palasy. Maternal complication are that also increased such as: preeclampsia, diabetes, maternal death...

We analyze the relationship between prenatal WIC participation and birth outcomes in New York City from 1988-2001. The analysis is unique for several reasons. First, we restrict the analysis to women on Medicaid and or WIC who have no previous live births and who initiate prenatal care within the first four months of pregnancy. Our goal is to lessen heterogeneity between WIC and nonWIC particip...

Intrauterine growth restriction (IUGR) is interconnected with developmental programming of lifelong pathophysiology. IUGR is seen in human multifetal pregnancies, with stepwise rises in fetal numbers interfering with placental nutrient delivery. It remains unknown whether fetal blood analyses would reflect fetal nutrition, liver, and excretory function in the last trimester of human or ovine IU...

Risk of birth defects in multiple pregnancies Frequency of monozygotic twins remains constant, while dizygotic twins become more frequent as maternal age increases. In these cases the risk that at least one fetus is aneuploid will be twice the maternal age risk for a singleton while the probability of both fetuses being involved is minimal. Dizygotic twins have a six fold increased risk that on...