We hereby report a case of hemorrhagic macular infarction after intravitreal bevacizumab for chronic multifocal central serous chorioretinopathy (CSC). Issues regarding safety and adverse effects of bevacizumab are discussed. To the best of our knowledge, this is the first reported case of hemorrhagic macular infarction after intravitreal bevacizumab for chronic multifocal CSC.

A 75-year–old patient was referred with vaginal bleeding. Her physical exam showed two flat dark plaques on the posterior fourchette, mostly on left lateral side of the vulva. A black soft mucosal nodule was present on the left lateral side of upper vagina, and a polypoid ulcerative cervical lesion extended into the right parametrium. Cervical and vaginal biopsies were in favor of malignant mel...

BACKGROUND Standard examination of contrast sensitivity under conditions of glare disability is performed with incandescent light. A new halogen glare test that simulates glare as seen with oncoming vehicle headlights was used to measure glare disability in patients implanted with multifocal and monofocal intraocular lenses (IOLs). METHODS 28 patients with an average age of 69 years (SD 12 ye...

Presbyopia is the gradual inability to focus near objects with age. This study explores patients’ attitudes and beliefs towards presbyopia including preferred modes of refractive correction. In United Kingdom, twenty-four volunteers completed an online questionnaire attended a structured, recorded group. Participants’ age ranged between 36 48 years, representing pre-presbyopic presbyopic popula...

PURPOSE To evaluate rotational stability and its influence on postoperative visual acuity of different monofocal and multifocal toric intraocular lenses (IOLs). METHODS A prospective interventional study was designed. Ninety-one patients with a mean age of 71.65 ± 11.82 years were implanted with toric IOLs after phacoemulsification. Three monofocal toric IOLs (the Lentis LT [Oculentis, Berlin...

PURPOSE Renal cell carcinomas are often multifocal. We investigated the genomic signatures of multifocal clear cell renal cell carcinoma to determine whether multiple tumors in the same kidney bear a clonal relationship to one another. EXPERIMENTAL DESIGN A total of 62 tumors from 26 patients who underwent radical nephrectomy were examined. All patients had multiple separate clear cell renal ...

BACKGROUND Initially based on histology, the diagnosis of renal artery fibromuscular dysplasia (FMD) is now based mostly on angiographic appearance because arterial tissue samples are rarely available. This retrospective cross-sectional study aimed to assess the clinical relevance of a binary angiographic classification of FMD lesions (unifocal or multifocal) based on computed tomographic or ma...

1. Wagner S, Conrad F, Bakaraju RC, Fedtke C, Ehrmann K, Holden BA. Power profiles of single vision and multifocal soft contact lenses. Cont Lens Anterior Eye. 2014;38:2--14. 2. Plainis S, Atchison DA, Charman WN. Power profiles of multifocal contact lenses and their interpretation. Optom Vis Sci. 2013;90:1066--1077. 3. Joannes L, Hough T, Hutsebaut X, et al. The reproducibility of a new power ...

We present a rare case of multifocal Proteus mirabilis osteomyelitis in an HIV-positive patient. Despite the patient's good immune status as assessed by her CD4 cell count and the aggressive treatment, she eventually underwent bilateral above-knee amputations to eradicate the infection. Multifocal Proteus mirabilis osteomyelitis can have an unpredictable clinical course with a severe outcome in...

Multifocal idiopathic fibrosclerosis is an uncommon systemic illness characterized by exuberant fibrosis involving diverse organs. Association between retroperitoneal fibrosis and pancreatic fibrosis is rare, but has been described previously. Here, we report a case of multifocal idiopathic fibrosclerosis with retroperitoneal fibrosis, pancreatic fibrosis and bronchiolitis obliterans with organ...