Pseudomonas aeruginosa (P. aeruginosa) infections occur mostly in children immunocompromised by chronic glucocorticoids, immunosuppressive agents, or immune deficiency. When P. aeruginosa disease occurs in previously healthy children, it progresses rapidly, and most patients die of septic multiorgan failure. This case describes a 9-month-old previously healthy girl who presented with cough, fev...

Results All these adult patients hailed from the rural Telangana region of Andhra Pradesh. Eighteen out of 48 were farmers. The average duration of fever was 11days. Eschar was noted in only 12.5% patients. Cough and breathlessness occurred in 30% cases. Central nervous system manifestations in the form of drowsiness and seizures were seen in 25% cases. Signs of consolidation were seen in 40% o...

A 53-year-old prisoner died of multiorgan failure after a suicidal overdose with 3,4-methylenedeoxymethamphetamine (MDMA, 'Ecstasy'). Twelve hours after ingestion of MDMA, the patient became severely hyperthermic (107.2 degrees F) with evidence of rhabdomyolysis. He subsequently developed acute respiratory distress syndrome (ARDS), disseminated intravascular coagulopathy (DIC) and acute renal f...

Fulminant hepatic failure (FHF) is a true medical emergency. It is a clinical syndrome characterized by the appearance of sudden marked impairment of liver cell function with hepatic encephalopathy, resulting from acute necrosis or dysfunction of a large portion of liver parenchyma. It is uncommon, but not rare. An estimated 2000 to 2500 deaths per year in the United States are due to FHF. Even...

Acute liver failure (ALF) is a life-threatening condition characterized by jaundice, encephalopathy and coagulopathy leading to multiorgan failure in a patient with no prior history of liver disease. Forty three consecutive patients of ALF admitted in Pediatric ICU were studied for etiology and prognostic factors. Etiology was established in 91% cases. Viral infections were the most common caus...

We report the case of 42-year-old male, who developed infective endocarditis on bicuspid aortic valve due to infection of the central line with Staphylococcus aureus MSSA. The patient was hospitalised several times in district hospitals because of worsening of heart failure. He had a few transthoracic (TTE) and one transesophageal (TEE) echocardiography which did not reveal early stages of p...

Acute liver failure (ALF) is a dramatic, highly unpredictable clinical syndrome defined by the sudden onset of coagulopathy and encephalopathy. Acetaminophen overdose, the leading cause of ALF in the United States, has a 66% chance of recovery with early N-acetylcysteine treatment and supportive care. Cerebral edema and infectious complications are difficult to detect and treat in these patient...

Pneumococcal intra-abdominal infections of female genital tract origin are rare. A 33-year-old woman with peritonitis due to Streptococcus pneumoniae serotype 3 was reported. The patient did not have any of the known predisposing conditions for intra-abdominal pneumococcal infection. The clinical presentation included signs of multiorgan failure. Peritoneal toilette, bilateral salpingectomy and...

The factor time plays an important role in diagnosis and treatment of acute aortic syndromes, not only as a short interval between diagnosis and surgical therapy, but also as a delay of definitive therapy in the selected cases. Severe organ damage caused by malperfusion or other mechanisms can be overcome by a surgical delay, improving prognosis. We report a successful attempt of a controlled d...