A variety of novel surgical approaches have been developed in recent years to manage disease of the cranial base. Few offer the width and depth of exposure achievable with the extended transbasal approach. This approach combines a bifrontal craniotomy with an orbitonasal or orbitonasoethmoidal osteotomy, and potentially a sphenoethmoidotomy to provide broad access to malignancies of the anterio...

Introduction: VZV is a human neurotropic alpha herpes virus, and humans are the only reservoir. Infection can involve any part of nervous system. The incidence neurological manifestations associated with 1-3 per 10,000 cases.
 clinical varicella-zoster virus (VZV) infections central system (CNS) include aseptic meningitis, encephalitis, cerebral infarction granulomatous vasculitis, myeliti...

Abstract BACKGROUND AND IMPORTANCE Third nerve palsies in the pediatric population are most commonly caused by trauma, tumors, or vascular abnormalities. Cystic oculomotor neuropathies, however, rare. We report case of a symptomatic cyst along and within nerve, which has not been described previously. CLINICAL PRESENTATION Here, we 3-yr-old girl presenting with progressive painless palsy. A mag...

The material for this paper comprises four case reports, which must necessarily be presented in some detail, having regard to the points in which they resemble and differ from one another. The resemblance between these cases is close enough to suggest that they constitute a recognizable clinical syndrome. As to their aetiology, the data permit no definite conclusion but suggest the possibility ...

Most peripheral neuropathies are length dependent and result in distal axonal degeneration rather than loss of neuronal cell bodies. Available therapies for axonal peripheral neuropathies are designed to control painful symptoms and not to treat the underlying axonal degeneration. Many neuroprotective therapies are being developed, primarily for central nervous system disorders such as stroke o...