PURPOSE To gain further insight into the pathogenesis of progressive facial hemiatrophy, a sporadic disease of unclear etiology characterized by shrinking and deformation of one side of the face. METHODS We investigated possible brain involvement. MR of the head and face was performed in three female patients with progressive facial hemiatrophy. The central-nervous-system findings were correl...

Cornelia de Lange syndrome (CdLS) is a rarely seen multisystem developmental disorder syndrome characterized by facial dysmorphia (arched eyebrows, synophrys, depressed nasal bridge, long philtrum, down-turned angles of the mouth), upper-extremity malformations, hirsutism, cardiac defects, growth and cognitive retardation, and gastrointestinal abnormalities. We present here a case of newborn ma...

Cardio-facio-cutaneous (CFC) syndrome is a rare disorder characterized by craniofacial dysmorphia, ectodermal abnormalities, cardiac malformations, as well as growth and developmental delay. Although some endocrine abnormalities have been reported in this syndrome, very little is known about CFC syndrome-related endocrine disorders. A 7.5-year-old boy was admitted to our endocrinology clinic wi...

CASE REPORT We report the clinical and radiologic observation in a man patient of 20 years old. He developed gravity left progressive facial hemiatrophy. In associated form, he presented numerous visual sensories and complex partials seizures. The single and combined treatment with several antiepileptic drugs was ineffective for the control of the epilepsy. The magnetic resonance investigation ...

muscle biopsy has been used for a long time for diagnosis of muscular, nerurogenic and systemic disorders with muscle involvement, because only very few of these disorders show sufficient specific clinical features for definite diagnosis. since the presence of difficulties in the screening of numerous genes, muscle biopsy could be a time and cost effective procedure for solving the diagnostic p...

introduction hemangiomas are the most common benign tumor of infancy that can occur anywhere in the body. intramuscular hemangiomas (imh) are accounting for approximately 1% of all cases and the muscles of extremities are the most common sites. because of scarcity and variable clinical features of these tumors, we decided to report a case of imh in the upper lip mucosa. case report the patient ...

smoking has been shown to be a complicating factor in normal wound healing. both nicotine and carbon monoxide adversely affect multiple stages of the healing process. from 1991 to 1999,407 muscle flap procedures were performed on 374 patients in a single surgical unit. a retrospective review of 261 patients was completed. patients were divided into three groups: group a, no smoking history grou...

Objective(s): Pregabalin (PGB) is a new antiepileptic drug that has received FDA approval for patient who suffers from central neuropathic pain, partial seizures, generalized anxiety disorder, fibromyalgia and sleep disorders. This study was undertaken to evaluate the possible adverse effects of PGB on the muscular system of mice. Materials and Methods: To evaluate the effect of PGB on skeletal...