When the Ballista project started in 1996 as a 3-year DARPA-funded research project, the original goal was to create a Web-based testing service to identify robustness faults in software running on client computers via the Internet. Previous experience suggested that such tests would find interesting problems but it was unclear how to make robustness testing scalable to large interfaces. A majo...

The aim of this work was to analyse the effects of different growth conditions (phosphate and contemporary carbon-phosphate starvation) on polystyrene adhesion of a strain of Pseudomonas aeruginosa ATCC 27853 and its four phenotypic mutants during experimental growth in starvation conditions. Bacterial adhesion was measured at 20, 40, 60 and 720 min. Data obtained showed that growth conditions ...

The current classification of acute myeloid leukemia (AML) relies largely on genomic alterations. AML with mutated nucleophosmin 1 (NPM1-mut) is the largest genetically defined groups, involving about 30% adult AMLs and currently recognized as a distinct entity in actual classifications. NPM1-mut usually occurs de novo associated predominantly normal karyotype relatively favorable prognosis. Ho...

Oncogenic RAS-induced reactive oxygen species (ROS) trigger barriers to cell transformation and cancer progression through tumor-suppressive responses such as cellular senescence or cell death. We have recently shown that oncogenic RAS-induced DNA damage and attendant premature senescence can be prevented by overexpressing human MutT Homolog 1 (MTH1), the major mammalian detoxifier of the oxidi...

The ability to control the physiological and pharmacological properties of synaptic receptors is a powerful tool for studying neuronal function and may be of therapeutic utility. We designed a recombinant adenovirus to deliver either a GABA(C) receptor rho(1) subunit or a mutant GABA(A) receptor beta(2) subunit lacking picrotoxin sensitivity [beta2(mut)] to hippocampal neurons. A green fluoresc...

While there have been many studies examining the stability of hierarchical triple systems, meaning ``stability'' is somewhat vague and has interpreted differently in previous literatures. The present paper focuses on ``Lagrange stability'', which roughly refers to against escape a body from system, or ``disruption'' contrast ``Lyapunov-like stability'' that related chaotic nature system dynamic...