The objective of the current study is to assess feasibility using a left ventricle (LV) model in order reproduce myocardial strains case ischemic heart disease (IHD). proposed integrated LV couples finite element method (FEM) sub-model cardiac electrical activity, representing propagation transmembrane potential through LV, FEM mechanical and lumped-parameter circulatory system that improves ph...

In the experimental animal the basic and controversial problem was studied of the influence of cardiac contraction on coronary blood flow. Normally beating hearts were perfused at a constant pressure, and coronary inflow and outflow were determined. In order to assess the role of systole, prolonged periods of ventricular asystole and fibrillation were induced and observations were made of the c...

In the experimental animal the basic and controversial problem was studied of the influence of cardiac contraction on coronary blood flow. Normally beating hearts were perfused at a constant pressure, and coronary inflow and outflow were determined. In order to assess the role of systole, prolonged periods of ventricular asystole and fibrillation were induced and observations were made of the c...

The effects of change in the concentration of Ca++ on myocardial contractility depressed by thiamylal and halothane were studied in isolated dog heart muscle. The concentration of Ca++ in the bathing medium was increased stepwise from 1.9 to 20.9 mM. An increase in Ca++ concentration resulted in an increase both in net-shortening (delta1) and in maximum velocity of shortening at 0.4 g preload (...

BACKGROUND Some patients referred for pharmacological stress testing with transthoracic echocardiography (TTE) are unable to undergo testing owing to poor acoustic windows. Fast cine MRI can be used to assess left ventricular contraction, but its utility for detection of myocardial ischemia in patients poorly suited for echocardiography is unknown. METHODS AND RESULTS One hundred fifty-three ...

The heart's physiological performance, unlike that of skeletal muscle, is regulated primarily by variations in the contractile force developed by the individual myocardial fibers. In an attempt to identify the basis for the characteristic properties of myocardial contraction, the individual cardiac contractile proteins and their behavior in contractile models in vitro have been examined. The lo...

Wall stress has been used as one of the parameters of myocardial mechanics. The present review focuses on recently developed data on ventricular wall stress, especially in relation to other newly developed areas in cardiology. In hypertensive hearts, there is a broad continuous spectrum in the structural and functional changes: those with low wall stress (inappropriate hypertrophy), those with ...

The time-motion representation of the echogram was used to evaluate the left ventricular posterior wall motion in myocardial infarction. The left ventricular posterior wall echo was obtained in 10 normal subjects and 26 patients with chest pain admitted to a coronary care unit, including 11 with acute myocardial infarction (group 1), nine with old myocardial infarction (group 2), and six with c...