The complete mol-ecules of the title compounds, N2,N5-bis-(pyridin-2-ylmeth-yl)pyrazine-2,5-dicarboxamide, C18H16N6O2 (I), 3,6-dimethyl-N2,N5-bis-(pyridin-2-yl-meth-yl)pyrazine-2,5-dicarboxamide, C20H20N6O2 (II), and N2,N5-bis-(pyridin-4-ylmeth-yl)pyrazine-2,5-dicarboxamide, C18H16N6O2 (III), are generated by inversion symmetry, with the pyrazine rings being located about centres of inversion. ...

BACKGROUND In laboratory mice and rats, congenic breeding is essential for analyzing the genes of interest on specific genetic backgrounds and for analyzing quantitative trait loci. However, in theory it takes about 3-4 years to achieve a strain carrying about 99% of the recipient genome at the tenth backcrossing (N10). Even with marker-assisted selection, the so-called 'speed congenic strategy...

Objective: To determine whether 2 dog breeds with a high risk for parvoviral enteritis, a disease associated with sepsis, produce stronger pro-inflammatory cytokine responses to a stimulus than dogs with a lower risk. Design: Blinded comparison. Setting: University outpatient clinic. Animals: Healthy, unrelated, purebred Doberman Pinschers (n5 10) and Rottweilers (n5 9) with agematched mixed-br...

Penelitian ini bertujuan untuk menyeleksi dan mendapatkan isolat jamur endofit dari tanaman nipah (Nypa fruticans) yang berdaya antagonis tinggi terhadap G. boninense penyebab penyakit busuk pangkal batang (BPB) pada kelapa sawit secara in vitro serta mengidentifikasinya hingga tingkat genus. dilakukan di Laboratorium Penyakit Tanaman Fakultas Pertanian Universitas Riau dimulai November 2020 Fe...

conformations and electronic properties of a series of imidazobenzodiazepines are investigated by am1 semi-empirical quantum mechanics method. it is shown that substitution of cl in position 7 instead of 8, changes the geometry of the seven membered lactam ring; this may put the n5 nitrogen in a better positon to act as a hydrogen bond acceptor, and the phenyl ring in position 6 is probably mor...

A new compounds named 3-4′-bipyrazoles 2 and 3 were synthesized in high chemical yield from a reaction of pyran-2,4-diketone 1 with aryl hydrazines under thermal conditions MeOH. Compound was unambiguously confirmed by single-crystal X-ray analysis. It crystalizes triclinic crystal system space group P-1. Its structure found to be good agreement the spectral characterizations. With aid Hirshfel...