نتایج جستجو برای: nadph د
تعداد نتایج: 27519 فیلتر نتایج به سال:
Nitric oxide plays a key role in the regulation of various female reproductive processes such as ovulation, implantation and myometrial relaxation. The aim of the present study was to determine the histochemical activity and cellular localization of NADPH-d in the porcine uterus during early pregnancy, including the implantation period. Tissue samples collected from the pig uteri on days 5, 10,...
Reactive oxygen intermediates (ROI) play an important role in cell signaling in addition to their role in microbial killing. We have shown previously that exogenous ROI regulate activity of the enzyme 5-lipoxygenase (5-LO) in alveolar macrophages (AM). Here, we examined the role of endogenous ROI, specifically generated by NADPH oxidase, in the regulation of leukotriene (LT) synthetic capacity ...
Renal hypertrophy and extracellular matrix accumulation are early features of diabetic nephropathy. Hyperglycemia-induced oxidative stress is implicated in the etiology of diabetic nephropathy. Resveratrol has potent antioxidative and protective effects on diabetic nephropathy. We aimed to examine whether high glucose (HG)-induced NADPH oxidase activation and reactive oxygen species (ROS) produ...
The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that are recruited by cancer cells, accumulate locally and systemically in adva...
The NADPH-diaphorase (NADPH-d) histochemical technique is commonly used to localize the nitric oxide (NO)-producing enzyme NO synthase (NOS) in neural tissues. In the olfactory tissues of vertebrates, however, NADPH-d staining can be present without the detection of NOS by other methods. We used pharmacological controls to determine whether NADPH-d staining was indicative of NOS in olfactory ti...
Oxidative stress plays a critical role in the vascular complications of type 2 diabetes. We examined the effect of type 2 diabetes on NADPH oxidase in human vessels and explored the mechanisms of this interaction. Segments of internal mammary arteries (IMAs) with their perivascular adipose tissue (PVAT) and thoracic adipose tissue were obtained from 386 patients undergoing coronary bypass surge...
introduction: the possible effect of postnatal chemically induced hypothyroidism on nadph- diaphorase containing neurons in different cortical areas of rat neonates. materials and methods: after parturition, dams divided in two groups. the control group receiving drinking water, and experimental group receiving 0.1% ptu in their drinking water. in different postnatal days (p4, p7, p10, p15, p23...
Background: Metabolic pathway operation and NAPDH homeostasis in non-growing bacteria is unknown. Results: Newly discovered metabolic cycles and known metabolic reactions balance concertedly the catabolic NADPH production. Conclusion: We propose the first quantitative NADPH balancing model under non-growing conditions. Significance: NADPH balancing is significantly different between resting and...
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