Non-alcoholic fatty liver disease (NAFLD) is now recognised as the hepatic component of metabolic syndrome (MetS). NAFLD is an example of ectopic fat accumulation in a visceral organ that causes organ-specific disease, and affects risk of other related diseases such as type 2 diabetes and CVD. NAFLD is a spectrum of fat-associated liver conditions that can culminate in end stage liver disease, ...

We prospectively assessed the impact of a sterol regulatory element-binding factor-2 (SREBF-2) polymorphism on the risk of developing nonalcoholic fatty liver disease (NAFLD) and on liver histology and lipoprotein and glucose metabolism in biopsy-proven NAFLD. In a population-based study, we followed 175 nonobese, nondiabetic participants without NAFLD or metabolic syndrome at baseline, charact...

To the Editor: We read with interest the recent article by Chang et al. (1 ) reporting that higher serum alanine aminotransferase (ALT) concentrations, within the reference interval, independently predicted the incidence of nonalcoholic fatty liver disease (NAFLD) during a mean follow-up of 2.5 years in a large cohort of apparently healthy Korean men. Several prospective studies have previously...

BACKGROUND Recent studies have suggested the importance of non-alcoholic fatty liver disease (NAFLD) and systemic inflammation in the development of atherosclerosis. The aim of this study was to compare the risk for coronary artery calcification (CAC) development according to the status of NAFLD and inflammation over four years of follow-up in subjects without baseline CAC. METHODS A total of...

conclusions it seems that hp eradication per se might not affect lfc, lft, lipid profile, and insulin resistance in dyspeptic nafld patients. results one hundred (49 males) patients with the mean age of 43.46 (± 11.52) were studied. repeated measure anova showed a significant reduction in lfc, anthropometric measurements, and laboratory parameters (except for hdl) in the both groups during the ...

nonalcoholic fatty liver disease (nafld) is an obesity-associated disease and dysregulation of adipokines has an important role in its development. omentin-1 (itln1 protein) and resistin are two adipokine secreted from adipose tissue. single nucleotide polymorphisms in the adipokine genes may affect expression and activity of the adipokine, and thus play a contributory role in nafld pathogenesi...

Introduction: Non-alcoholic fatty liver disease (NAFLD) has become the most common cause of liver disease worldwide. It has been suggested that dietary composition plays a role in NAFLD pathogenesis; thus, changing dietary patterns may constitute a therapeutic resource even in the absence of weight reduction. The aim of this study was to identify the characteristic of suitable dietary pattern i...

Non-alcoholic fatty liver disease (NAFLD) is rapidly emerging as a leading etiology of chronic (CLD) in Asia. The increasing incidence NAFLD projected to drive surge NAFLD-related hepatocellular carcinoma (HCC). A notable characteristic NAFLD-HCC its capacity for development individuals without cirrhosis more than third patients. Most practice guidelines recommend biannual ultrasound screening ...

OBJECTIVE Patients with type 2 diabetes and nonalcoholic fatty liver disease (NAFLD) have a higher prevalence of cardiovascular diseases. In this study we investigated the frequency of single nucleotide polymorphisms (SNPs) of several candidate genes associated with NAFLD in Taiwanese patients with type 2 diabetes mellitus (DM) and NAFLD and in those with DM but without fatty liver disease. M...

Nonalcoholic fatty liver disease (NAFLD) and resulting nonalcoholic steatohepatitis (NASH) are highly prevalent in the United States, where they are a growing cause of cirrhosis and hepatocellular carcinoma (HCC) and increasingly an indicator for liver transplantation. A Markov model was used to forecast NAFLD disease progression. Incidence of NAFLD was based on historical and projected changes...